Gastrointestinal bioaccessibility and bioactivity of phenolic compounds from araca-boi fruit

Autor(es)

de Araujo, Fabio Fernandes ^[1] ; Farias, David de Paulo ^[1] ; Neri-Numa, Iramaia Angelica ^[1] ; Dias-Audibert, Flavia Luisa ^[2] ; Delafiori, Jeany ^[2] ; de Souza, Florisvaldo Gama ^[1] ; Catharino, Rodrigo Ramos ^[2] ; do Sacramento, Celio Kersul ^[3] ; Pastore, Glaucia Maria ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Fac Food Engn, Dept Food Sci, Bioflavors & Bioact Cpds Lab, Campinas, SP - Brazil

^[2] Univ Estadual Campinas, Sch Pharmaceut Sci, INNOVARE Biomarkers Lab, Campinas, SP - Brazil

^[3] Univ Estadual Santa Cruz, Dept Agr & Environm Sci, Ilheus, BA - Brazil

• Tipo de documento: Artigo Científico
• Fonte: LWT-FOOD SCIENCE AND TECHNOLOGY; v. 135, JAN 2021.
• Citações Web of Science: 0

Resumo

In this study, we evaluated for the first time the bioaccessibility and bioactivity of phenolic compounds present in fractions of araca-boi submitted to the in vitro gastrointestinal digestion. For this, were determined the content of phenolics and total flavonoids, antioxidant capacity, as well as heatmap analysis to evaluate the relative intensity of the phenolic compounds identified by ESI-LTQ-XL-MS/MS, before and after digestive process. It was observed that the seed had the highest amount of total phenolic compounds, and that this content was reduced after digestion, mainly in the intestinal phase (-22.0%), while the flavonoid content increased in the edible fraction (92.8%). From the ESI-LTQXL-MS/MS analysis, it was possible to identify 9 flavonoids and 8 phenolic acids in the edible fraction, while in the seed 10 flavonoids and 7 phenolic acids were identified. Heatmap analysis demonstrated that after intestinal digestion, phenolic acids reduced and flavonoids increased their relative intensity, suggesting that these compounds increased their content after this process. The seed showed the highest antioxidant capacity and in general this potential increased after digestion. Thus, the bioaccessibility and bioactivity of the phenolic compounds of araca-boi can be influenced by the fraction and digestive phase evaluated. (AU)

• Processo FAPESP: 20/00225-6 - Determinação do potencial antioxidante, bioacessibilidade in vitro e avaliação das atividades antidiabética e prebiótica da uvaia (Eugenia pyriformis Cambess)
• Beneficiário: David de Paulo Farias
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 19/05718-3 - Determinação das alterações metabólicas e do potencial terapêutico do Zika Vírus em células tumorais por espectrometria de massas e inteligência artificial
• Beneficiário: Jeany Delafiori
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto