A novel dispersive liquid-liquid microextraction using a low density deep eutectic solvent-gas chromatography tandem mass spectrometry for the determination of polycyclic aromatic hydrocarbons in soft drinks

Autor(es)

Caldeirao, Lucas ^{[1, 2]} ; Fernandes, Jose O. ^[2] ; Gonzalez, Mario Henrique ^[3] ; Godoy, Helena Teixeira ^[1] ; Cunha, Sara C. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Campinas UNICAMP, Fac Food Engn, BR-13083862 Campinas, SP - Brazil

^[2] Univ Porto, Lab Bromatol & Hydrol, LAQV REQUIMTE, Fac Pharm, Porto - Portugal

^[3] Sao Paulo State Univ UNESP, Natl Inst Alternat Technol Detect Toxicol Evaluat, Dept Chem & Environm Sci, BR-15054000 Sao Josedo Do Rio Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Chromatography A; v. 1635, JAN 4 2021.
• Citações Web of Science: 1

Resumo

Ready-to-drink teas can provide, if properly packaged, the taste and wellness character of traditional teas. Nevertheless, in tea processing, there may be several contaminations, among which polycyclic aromatic hydrocarbons (PAHs), anthropogenic contaminants that can present carcinogenic and mutagenic properties. In this work, a novel low-density deep eutectic solvent-based dispersive liquid-liquid microextraction (LDDES-DLLME) procedure followed by gas chromatography tandem mass spectrometry (GC-MS/MS) was optimized for analysis of 15 polycyclic aromatic hydrocarbons (PAHs) in ready-to-drink herbal-based beverages. The new deep eutectic solvent (DES) was synthesized with natural compounds (camphor and hexanoic acid). Several parameters of the extraction procedure such as type and volume of extraction solvent, type, volume of dispersive solvent, and time of extraction were evaluated to achieve the highest yield and to attain the lowest detection limits. The validated method showed very low limits of detection (0.01 mu g L-1) and quantification (0.2 mu g L-1), good interand intra-day precisions (RSD < 16.87%), and recoveries higher than 69%. The method was applied to 16 type of samples and it was found total PAHs levels ranging from 0.20 to 1.82 mu g L-1. The developed LDDES-DLLME showed a reliable and innovative alternative for the extraction of PAHs from beverages, cost-effective and environmentally friendly, and providing a satisfactory throughput. (C) 2020 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 17/18531-3 - Química analítica verde: do preparo de amostras a determinações de elementos-traço por espectrometria de massas com plasma indutivamente acoplado (ICP-MS)
• Beneficiário: Mario Henrique Gonzalez
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/05048-2 - Plantas tradicionalmente empregadas como infusão: Técnicas de preparo de amostra e determinação de contaminantes
• Beneficiário: Lucas Caldeirão Rodrigues Miranda
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 18/25746-9 - Aplicação de solventes eutéticos profundos em técnica de preparo de amostra para determinação de contaminantes em chás prontos para beber
• Beneficiário: Lucas Caldeirão Rodrigues Miranda
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
• Processo FAPESP: 19/22113-8 - Solventes eutéticos naturais: síntese, caracterização e aplicações na determinação de As, Cd, Cr, Hg, Se e V em amostras ambientais por ICP-MS
• Beneficiário: Mario Henrique Gonzalez
• Modalidade de apoio: Auxílio à Pesquisa - Regular