Electrohalogenation of organic compounds

Autor(es)

Scheide, Marcos R. ^[1] ; Nicoleti, Celso R. ^[1] ; Martins, Guilherme M. ^[1] ; Braga, Antonio L. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Santa Catarina UFSC, Dept Quim, BR-88040900 Florianopolis, SC - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: ORGANIC & BIOMOLECULAR CHEMISTRY; v. 19, n. 12, p. 2578-2602, MAR 28 2021.
• Citações Web of Science: 0

Resumo

Herein, we present an overview of recent advances in the electrochemical halogenation of organic compounds. Halogen-containing compounds are essential building blocks for post-functionalization in academic research and in different industrial sectors, notably pharmaceutical companies. One of the main advantages of using electrosynthesis is its environmentally-friendly characteristics. Electrosynthesis is recognized as a methodology that can fulfill different criteria of the green chemistry concept and constitutes a promising tool in the development of new procedures in organic synthesis. In this review we target sp, sp(2) and sp(3) carbon fluorination, chlorination, bromination and iodination reactions using electrolysis as a redox medium. Mechanistic insights and substrate reactivity are also discussed. (AU)

• Processo FAPESP: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
• Beneficiário: Arlene Gonçalves Corrêa
• Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia