| Full text | |
| Author(s): |
Total Authors: 4
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| Affiliation: | [1] Univ Fed Santa Catarina UFSC, Dept Quim, BR-88040900 Florianopolis, SC - Brazil
Total Affiliations: 1
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| Document type: | Review article |
| Source: | ORGANIC & BIOMOLECULAR CHEMISTRY; v. 19, n. 12, p. 2578-2602, MAR 28 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Herein, we present an overview of recent advances in the electrochemical halogenation of organic compounds. Halogen-containing compounds are essential building blocks for post-functionalization in academic research and in different industrial sectors, notably pharmaceutical companies. One of the main advantages of using electrosynthesis is its environmentally-friendly characteristics. Electrosynthesis is recognized as a methodology that can fulfill different criteria of the green chemistry concept and constitutes a promising tool in the development of new procedures in organic synthesis. In this review we target sp, sp(2) and sp(3) carbon fluorination, chlorination, bromination and iodination reactions using electrolysis as a redox medium. Mechanistic insights and substrate reactivity are also discussed. (AU) | |
| FAPESP's process: | 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock |
| Grantee: | Arlene Gonçalves Corrêa |
| Support Opportunities: | Research Grants - Research Centers in Engineering Program |