| Texto completo | |
| Autor(es): |
Gomes, Carolina Nogueira
[1]
;
Barker, Dillon Oliver Reese
[2]
;
Duque, Sheila da Silva
[3]
;
Che, Emily Victoria
[2]
;
Jayamanna, Vasena
[2]
;
Taboada, Eduardo Napoleon
[2]
;
Falcao, Juliana Pfrimer
[1]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmceut Ribeirao Preto, Ribeirao Preto, SP - Brazil
[2] Publ Hlth Agcy Canada, Natl Microbiol Lab, Winnipeg, MB - Canada
[3] Fundacao Oswaldo Cruz FIOCRUZ, Inst Oswaldo Cruz IOC, Rio De Janeiro - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | INFECTION GENETICS AND EVOLUTION; v. 95, NOV 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
Campylobacter has been one of the most common causative agent of bacterial food-borne gastroenteritis in humans worldwide. However, in Brazil the campylobacteriosis has been a neglected disease and there is insufficient data to estimate the incidence of this pathogen in the country. Aims: The current study aimed to determine the phylogenetic relationships among Campylobacter coli strains isolated in Brazil and to compare them with international Campylobacter isolates available in some public databases. Methods and results: A total of 63C. coli strains isolated in Brazil were studied. The MLST analysis showed 18 different STs including three STs not yet described in the PubMLST database. The cgMLST allocated the Brazilian strains studied into five main clusters and each cluster comprised groups of strains with nearly identical cgMLST profiles and with significant genetic distance observed among the distinct clusters. The comparison of the Brazilian strains with 3401 isolates from different countries showed a wide distribution of these strains isolated in this country. Conclusions: The results showed a high similarity among some strains studied and a wide distribution of the Brazilian strains when compared to isolates from different countries, which is an interesting data set since it showed a high genetic diversity of these strains from Brazil in a global context. This study contributed for a better genomic characterization of C. coli strains isolated in Brazil and provided important information about the diversity of this clinically-relevant pathogen. (AU) | |
| Processo FAPESP: | 18/26043-1 - Sequenciamento do genoma completo e análise genômica comparativa de linhagens de Campylobacter coli isoladas de diversas fontes durante 16 anos no Brasil |
| Beneficiário: | Carolina Nogueira Gomes |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Doutorado |
| Processo FAPESP: | 16/24716-3 - Sequenciamento do genoma, transcriptoma e análise fenotípica de linhagens de Campylobacter coli isoladas de diversas fontes no Brasil |
| Beneficiário: | Juliana Pfrimer Falcão |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 15/23408-0 - Análise fenotípica, sequenciamento do genoma e transcriptoma de linhagens de Campylobacter coli isoladas de diversas fontes durante 16 anos no Brasil |
| Beneficiário: | Carolina Nogueira Gomes |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 19/19338-8 - Genômica, transcriptômica e caracterização fenotipica de linhagens de Campylobacter jejuni isoladas de diversas fontes durante 20 anos no Brasil |
| Beneficiário: | Juliana Pfrimer Falcão |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |