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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Campylobacter coli isolated in Brazil typed by core genome Multilocus Sequence Typing shows high genomic diversity in a global context

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Author(s):
Gomes, Carolina Nogueira [1] ; Barker, Dillon Oliver Reese [2] ; Duque, Sheila da Silva [3] ; Che, Emily Victoria [2] ; Jayamanna, Vasena [2] ; Taboada, Eduardo Napoleon [2] ; Falcao, Juliana Pfrimer [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmceut Ribeirao Preto, Ribeirao Preto, SP - Brazil
[2] Publ Hlth Agcy Canada, Natl Microbiol Lab, Winnipeg, MB - Canada
[3] Fundacao Oswaldo Cruz FIOCRUZ, Inst Oswaldo Cruz IOC, Rio De Janeiro - Brazil
Total Affiliations: 3
Document type: Journal article
Source: INFECTION GENETICS AND EVOLUTION; v. 95, NOV 2021.
Web of Science Citations: 0
Abstract

Campylobacter has been one of the most common causative agent of bacterial food-borne gastroenteritis in humans worldwide. However, in Brazil the campylobacteriosis has been a neglected disease and there is insufficient data to estimate the incidence of this pathogen in the country. Aims: The current study aimed to determine the phylogenetic relationships among Campylobacter coli strains isolated in Brazil and to compare them with international Campylobacter isolates available in some public databases. Methods and results: A total of 63C. coli strains isolated in Brazil were studied. The MLST analysis showed 18 different STs including three STs not yet described in the PubMLST database. The cgMLST allocated the Brazilian strains studied into five main clusters and each cluster comprised groups of strains with nearly identical cgMLST profiles and with significant genetic distance observed among the distinct clusters. The comparison of the Brazilian strains with 3401 isolates from different countries showed a wide distribution of these strains isolated in this country. Conclusions: The results showed a high similarity among some strains studied and a wide distribution of the Brazilian strains when compared to isolates from different countries, which is an interesting data set since it showed a high genetic diversity of these strains from Brazil in a global context. This study contributed for a better genomic characterization of C. coli strains isolated in Brazil and provided important information about the diversity of this clinically-relevant pathogen. (AU)

FAPESP's process: 18/26043-1 - Whole genome sequencing and comparative genomics of Campylobacter coli strains isolated from different sources over a 16 year-period in Brazil
Grantee:Carolina Nogueira Gomes
Support Opportunities: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 16/24716-3 - Sequencing of the Genome, transcriptoma and phenotypic analysis of Campylobacter coli strains isolated from different sources in Brazil
Grantee:Juliana Pfrimer Falcão
Support Opportunities: Regular Research Grants
FAPESP's process: 15/23408-0 - Phenotypic analysis, genome and transcriptome sequencing of Campylobacter coli strains isolated from different sources during 16 years in Brazil
Grantee:Carolina Nogueira Gomes
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 19/19338-8 - Genomic, transcriptomic and phenotypic characterization of Campylobacter jejuni strains isolated from diverse source during 20 years in Brazil
Grantee:Juliana Pfrimer Falcão
Support Opportunities: Regular Research Grants