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(Referência obtida automaticamente do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Investigation of a modified hydraulic calcium silicate-based material – Bio-C Pulpo

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Autor(es):
Lauter Eston PELEPENKO [1] ; Flávia SAAVEDRA [2] ; Thiago Bessa Marconato ANTUNES [3] ; Gabriela Fernanda BOMBARDA [4] ; Brenda Paula Figueiredo de Almeida GOMES [5] ; Alexandre Augusto ZAIA [6] ; Marina Angélica MARCIANO [7]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Universidade Estadual de Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[2] Universidade Estadual de Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[3] Universidade Estadual de Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[4] Universidade Estadual de Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[5] Universidade Estadual de Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[6] Universidade Estadual de Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
[7] Universidade Estadual de Campinas. Piracicaba Dental School. Department of Restorative Dentistry - Brasil
Número total de Afiliações: 7
Tipo de documento: Artigo Científico
Fonte: Brazilian Oral Research; v. 35, 2021-06-16.
Resumo

Abstract This study evaluated the physicochemical, biological, and antimicrobial properties of a new hydraulic calcium silicate-based modified material, and compared it with MTA Repair HP and MTA Angelus. The materials were assessed regarding color luminosity (L), color change, radiopacity, setting time, and ISO 6876:2012 linear flow. Volumetric filling and volume change were evaluated using microcomputed-tomography (µCT). Chemical characterization after 28 days in Hank’s Balanced Salt Solution (HBSS) and pH analysis were also assessed. Biological characterization of cytotoxicity and microbiological assessment were also undertaken. Shapiro-Wilk, ANOVA, Levene and post hoc analyses with Bonferroni correction were performed, adopting a 5% significance level (p <0.05). Bio-C Pulpo exhibited the highest L values after 90 days. All tested materials demonstrated color change during the analyses, and had radiopacity above 5 mm Al. MTA Repair HP set faster than Bio-C Pulpo, whereas the latter had the highest linear flow. MTA Repair HP had the highest volumetric filling in µCT analysis. Bio-C Pulpo showed the highest alkalinity during all tested periods, and the highest volumetric loss (above 9%), in comparison with MTA Repair HP and MTA Angelus. Bio-C Pulpo did not form calcium hydroxide after hydration. MTA Repair HP demonstrated the highest cytocompatibility, and Bio-C Pulpo, the highest cytotoxicity. No inhibition halos were observed for any material, and similar higher turbidity values were seen after direct contact. Composition additives used in Bio-C Pulpo modified its properties, and both the absence of calcium hydroxide deposition after hydration, and the related cytotoxicity of this material are of particular concern. (AU)

Processo FAPESP: 17/05096-7 - Avaliação das propriedades físicas, químicas e antimicrobianas de um novo cimento reparador de alta plasticidade
Beneficiário:Marina Angélica Marciano da Silva
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 18/06515-6 - Caracterização química e estrutural de cimentos reparadores de alta plasticidade
Beneficiário:Gabriela Fernanda Bombarda
Linha de fomento: Bolsas no Brasil - Iniciação Científica
Processo FAPESP: 18/16722-9 - Padrões de difração de cimentos reparadores de alta plasticidade
Beneficiário:Gabriela Fernanda Bombarda
Linha de fomento: Bolsas no Exterior - Estágio de Pesquisa - Iniciação Científica
Processo FAPESP: 17/18413-0 - Avaliação da bioatividade, escoamento, pH e liberação de íons cálcio de cimentos reparadores de alta plasticidade
Beneficiário:Thiago Bessa Marconato Antunes
Linha de fomento: Bolsas no Brasil - Iniciação Científica