Recent Developments on Palladium-Catalyzed Carbonylation Reactions in Renewable Solvents

Autor(es)

Danilo Y. de Albuquerque ^[1] ; Wystan K. O. Teixeira ^[2] ; Senthil Narayanaperumal ^[3] ; Ricardo S. Schwab ^[4]

Afiliação do(s) autor(es)

^[1] Universidade Federal de São Carlos (UFSCar). Centro de Excelência para Pesquisa em Química Sustentável (CERSusChem). Departamento de Química - Brasil

^[2] Universidade Federal de São Carlos (UFSCar). Centro de Excelência para Pesquisa em Química Sustentável (CERSusChem). Departamento de Química - Brasil

^[3] Libbs Farmacêutica Ltda. - Brasil

^[4] Universidade Federal de São Carlos (UFSCar). Centro de Excelência para Pesquisa em Química Sustentável (CERSusChem). Departamento de Química - Brasil

• Tipo de documento: Artigo Científico
• Fonte: Journal of the Brazilian Chemical Society; v. 33, n. 7, p. 637-663, 2022-06-17.

Resumo

Palladium-catalyzed carbonylation reaction has surfaced as a robust tool for insertion of the carbonyl group into organic molecules, and in the last decades enormous progress has been made. Nowadays, a plethora of methodologies is available to synthesize all kinds of carbonyl compounds. However, the focus has shifted during recent years to address rising concerns related to developing safe, cost-efficient, and more sustainable methodologies. The use of different carbon monoxide (CO) precursors/sources, avoiding handling of highly toxic and flammable gaseous carbon monoxide, and substituting nonrenewable solvents for those derived from renewable feedstock have contributed to aim these goals. In this review, we will discuss the advent of the application of renewable solvents to improve the sustainability and environmentally benign nature of Pd catalyzed carbonylation reactions. (AU)

• Processo FAPESP: 13/06558-3 - Catálise metálica assimétrica: preparação de alcoóis quirais e seus derivados a partir de reagentes orgânicos de zinco poli-funcionalizados e aplicação de novos ligantes quirais suportados em nanopartículas magnéticas
• Beneficiário: Ricardo Samuel Schwab
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
• Beneficiário: Arlene Gonçalves Corrêa
• Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia