Deficiency and Insufficiency of Vitamin D in Women of Childbearing Age: A Systematic Review and Meta-analysis

Autor(es)

Lucchetta, Rosa Camila ; Lemos, Isabele Held ; Gini, Ana Luisa Rodriguez ; Cavicchioli, Sophia de Andrade ; Forgerini, Marcela ; Varallo, Fabiana Rossi ; de Nadai, Mariane Nunes ; Fernandez-Llimos, Fernando ; Mastroianni, Patricia de Carvalho

• Tipo de documento: Artigo Científico
• Fonte: Revista Brasileira de Ginecologia e Obstetrícia; v. 44, n. 04, p. 16-pg., 2022-02-24.

Resumo

Objective To estimate the prevalence of inadequate vitamin D level and its associated factors for women of childbearing age in Brazil. Methods A systematic review was conducted (last updated May 2020). Meta-analyses were performed using the inverse-variance for fixed models with summary proportion calculation by Freeman-Tukey double arcsine. Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies. Results Our review identified 31 studies, comprising 4,006 participants. All the studies had at least one weakness, mainly due to the use of convenience sampling and small sample size. The overall prevalence of vitamin D deficiency, insufficiency, and both deficiency and insufficiency were 35% (confidence interval, 95%CI: 34-37%), 42% (95%CI: 41-44%), and 72% (95%CI: 71-74%), respectively. Conclusion Although the magnitude of the prevalence of inadequate levels of vitamin D is uncertain, the evidence suggests that presence of vitamin D deficiency or insufficiency in women of reproductive age can cause moderate to severe problems. (AU)

• Processo FAPESP: 18/07501-9 - Determinantes genéticos da hemorragia gastrointestinal associada ao uso do ácido acetilsalicílico como agente antiplaquetário: um estudo caso-controle
• Beneficiário: Marcela Forgerini
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto