| Texto completo | |
| Autor(es): |
Bocelli, Marcio David
;
Medina, Deyber Arley Vargas
;
Lancas, Fernando Mauro
;
dos Santos-Neto, Alvaro Jose
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ANALYTICAL AND BIOANALYTICAL CHEMISTRY; v. N/A, p. 12-pg., 2023-08-03. |
| Resumo | |
An automated microextraction by packed sorbent followed by liquid chromatography-tandem mass spectrometry (MEPS-LC-MS/MS) method was developed for the determination of four endocrine disruptors-parabens, benzophenones, and synthetic phenolic antioxidants-in wastewater samples. The method utilizes a lab-made repackable MEPS device and a multi-syringe robotic platform that provides flexibility to test small quantities (2 mg) of multiple extraction phases and enables high-throughput capabilities for efficient method development. The overall performance of the MEPS procedure, including the investigation of influencing variables and the optimization of operational parameters for the robotic platform, was comprehensively studied through univariate and multivariate experiments. Under optimized conditions, the target analytes were effectively extracted from a small sample volume of 1.5 mL, with competitive detectability and analytical confidence. The limits of detection ranged from 0.15 to 0.30 ng L-1, and the intra-day and inter-day relative standard deviations were between 3 and 21%. The method's applicability was successfully demonstrated by determining methylparaben, propylparaben, butylated hydroxyanisole, and oxybenzone in wastewater samples collected from the Sao Carlos (SP, Brazil) river. Overall, the developed method proved to be a fast, sensitive, reliable, and environmentally friendly analytical tool for water quality monitoring. (AU) | |
| Processo FAPESP: | 17/02147-0 - Cromatografia líquida em uma gota e seu acoplamento com espectrometria de massas: estratégias instrumentais, desenvolvimento de materiais, automatização e aplicações analíticas |
| Beneficiário: | Fernando Mauro Lanças |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 19/22724-7 - Novas estratégias instrumentais no desenvolvimento de métodos analíticos automatizados e miniaturizados para a determinação de compostos orgânicos mediante cromatografia líquida acoplada a espectrometria de massas |
| Beneficiário: | Deyber Arley Vargas Medina |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 15/15462-5 - Emprego do grafeno como material sorvente em técnicas miniaturizadas de preparo de amostra. |
| Beneficiário: | Bruno Henrique Fumes |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 14/07347-9 - Desenvolvimento de novos materiais e dispositivos para técnicas miniaturizadas de preparo de amostras na área de segurança alimentar |
| Beneficiário: | Fernando Mauro Lanças |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |