Characterization and stability of solid lipid nanoparticles produced from different fully hydrogenated oils

Autor(es)

Stahl, Marcella Aparecida ; Ludtke, Fernanda Luisa ; Grimaldi, Renato ; Gigante, Mirna Lucia ; Ribeiro, Ana Paula Badan

• Tipo de documento: Artigo Científico
• Fonte: Food Research International; v. 176, p. 17-pg., 2023-12-10.

Resumo

The use of lipids from conventional oils and fats to produce solid lipid nanoparticles (SLN) attracting interest from the food industry, since due their varying compositions directly affects crystallization behavior, stability, and particle sizes (PS) of SLN. Thus, this study aimed evaluate the potential of fully hydrogenated oils (hardfats) with different hydrocarbon chain lengths to produce SLN using different emulsifiers. For that, fully hydrogenated palm kern (FHPkO), palm (FHPO), soybean (FHSO), microalgae (FHMO) and crambe (FHCO) oils were used. Span 60 (S60), soybean lecithin (SL), and whey protein isolate (WPI) were used as emulsifiers. The physicochemical characteristics and crystallization properties of SLN were evaluated during 60 days. Results indicates that the crystallization properties were more influenced by the hardfat used. SLN formulated with FHPkO was more unstable than the others, and hardfats FHPO, FHSO, FHMO, and FHCO exhibited the appropriate characteristics for use to produce SLN. Concerning emulsifiers, S60- based SLN showed high instability, despite the hardfat used. SL-based and WPI-based SLN formulations, showed a great stability, with crystallinity properties suitable for food incorporation. (AU)

• Processo FAPESP: 16/11261-8 - Óleos, gorduras e nanotecnologia: desenvolvimento de nanopartículas lipidicas sólidas e carreadores lipídicos nanoestruturados para incorporação de compostos bioativos lipofílicos
• Beneficiário: Ana Paula Badan Ribeiro
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 19/27354-3 - Arquitetura de sistemas de liberação coloidais: qual é o papel da estrutura na digestibilidade?
• Beneficiário: Rosiane Lopes da Cunha
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 18/03172-0 - Desenvolvimento de carreadores lipídicos nanoestruturados para incorporação de compostos bioativos lipofílicos
• Beneficiário: Fernanda Luisa Lüdtke
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 19/05176-6 - Avaliação da digestibilidade in vitro de carreadores lipídicos nanoestruturados com incorporação de ²-caroteno
• Beneficiário: Fernanda Luisa Lüdtke
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado