Liposomes encapsulating beta-carotene produced by the proliposomes method: characterisation and shelf life of powders and phospholipid vesicles

Autor(es)

Moraes, Marilia ^[1] ; Carvalho, Jose Mario P. ^[1] ; Silva, Cintia R. ^[1] ; Cho, Stefany ^[1] ; Sola, Mirella R. ^[1] ; Pinho, Samantha C. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dept Food Engn, Fac Anim Sci & Food Engn, BR-13635900 Pirassununga, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY; v. 48, n. 2, p. 274-282, FEB 2013.
• Citações Web of Science: 38

Resumo

The objective of this study was to investigate the feasibility of producing proliposomes incorporating beta-carotene by spray drying and to assess the capacity of the liposomes produced by the hydration of the dry phospholipid particles to preserve the encapsulated carotenoid. Powders containing beta-carotene, hydrogenated phosphatidylcholine and sucrose were obtained and characterised in terms of crystallinity, morphology, thermal behaviour, density, solubility and hygroscopicity. The preservation of beta-carotene in the powder was evaluated for two storage conditions under normal atmosphere and vacuum. The proliposome was highly soluble, with all components embedded in the matrix and capable of preserving more than 90% of the incorporated beta-carotene for 60 days of refrigerated storage under vacuum. The liposome dispersions maintained their average size, polydispersity index and zeta potential for 100 days of storage. After 60 days, the degradation of encapsulated beta-carotene was minimal, and the colour of the dispersions was preserved. (AU)

• Processo FAPESP: 09/14868-7 - Estabilização de dispersões de lipossomas através do espessamento com de goma xantana
• Beneficiário: Jose Mário Pereira de Carvalho
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 09/01091-4 - Produção de lipossomas via hidratação de membranas secas de fosfolipídios: estudo de viabilidade e caracterização
• Beneficiário: Cintia Ribeiro da Silva
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 09/01087-7 - Incorporação de carotenóide em lipossomas por hidratação de partículas secas de fosfolipídios
• Beneficiário: Samantha Cristina de Pinho
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 08/09394-3 - Incorporação de betacaroteno em lipossomas via hidratação de partículas secas de fosfolipídios produzidas por atomização
• Beneficiário: Marília Moraes Lovison
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica