Malnutrition-Inflammation Score is Associated With Handgrip Strength in Nondialysis-Dependent Chronic Kidney Disease Patients

Autor(es)

Amparo, Fernanda C. ^{[1, 2]} ; Cordeiro, Antonio C. ^{[3, 4]} ; Carrero, Juan J. ^[4] ; Cuppari, Lilian ^[2] ; Lindholm, Bengt ^[4] ; Amodeo, Celso ^[3] ; Kamimura, Maria A. ^[2]

Afiliação do(s) autor(es)

^[1] Dante Pazzanese Inst Cardiol, Dept Nutr, BR-04012909 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Nutr Program, Sao Paulo - Brazil

^[3] Dante Pazzanese Inst Cardiol, Dept Hypertens & Nephrol, BR-04012909 Sao Paulo - Brazil

^[4] Karolinska Inst, Baxter Novum & Renal Med, Stockholm - Sweden

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF RENAL NUTRITION; v. 23, n. 4, p. 283-287, JUL 2013.
• Citações Web of Science: 15

Resumo

Objective: The malnutrition-inflammation score (MIS) is a nutritional scoring system that has been associated with muscle strength among dialysis patients. We aimed to test whether MIS is able to predict muscle strength in nondialysis-dependent chronic kidney disease (NDD-CKD) individuals. Design and Methods: This was a cross-sectional study conducted at the Dante Pazzanese Institute of Cardiology, Hypertension, and Nephrology Division outpatient clinic. We evaluated 190 patients with NDD-CKD stages 2-5 (median 59.5 {[}interquartile range 51.4-66.9] years; 64% men). MIS was calculated without computing dialysis vintage to the scoring. HGS was assessed in the dominant arm. Anthropometric, laboratory, and body composition parameters were recorded. Results: A strong negative correlation was found between HGS and MIS (r = -0.42; P <= .001) in univariate analysis. In multivariate regressions, adjustment for age, sex, diabetes, glomerular filtration rate, body cell mass, and C-reactive protein did not materially diminish these relationships. Conclusions: MIS shares strong links with objective measures of muscle strength in NDD-CKD patients. (C) 2013 by the National Kidney Foundation, Inc. All rights reserved. (AU)

• Processo FAPESP: 10/16593-2 - Associação de fatores de risco tradicionais, novos e relacionados à uremia com a doença aterosclerótica coronariana e a morbimortalidade geral e cardiovascular em pacientes com doença renal crônica
• Beneficiário: Antonio Carlos Cordeiro Silva Júnior
• Modalidade de apoio: Auxílio à Pesquisa - Regular