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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Malnutrition-Inflammation Score is Associated With Handgrip Strength in Nondialysis-Dependent Chronic Kidney Disease Patients

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Author(s):
Amparo, Fernanda C. [1, 2] ; Cordeiro, Antonio C. [3, 4] ; Carrero, Juan J. [4] ; Cuppari, Lilian [2] ; Lindholm, Bengt [4] ; Amodeo, Celso [3] ; Kamimura, Maria A. [2]
Total Authors: 7
Affiliation:
[1] Dante Pazzanese Inst Cardiol, Dept Nutr, BR-04012909 Sao Paulo - Brazil
[2] Univ Sao Paulo, Nutr Program, Sao Paulo - Brazil
[3] Dante Pazzanese Inst Cardiol, Dept Hypertens & Nephrol, BR-04012909 Sao Paulo - Brazil
[4] Karolinska Inst, Baxter Novum & Renal Med, Stockholm - Sweden
Total Affiliations: 4
Document type: Journal article
Source: JOURNAL OF RENAL NUTRITION; v. 23, n. 4, p. 283-287, JUL 2013.
Web of Science Citations: 15
Abstract

Objective: The malnutrition-inflammation score (MIS) is a nutritional scoring system that has been associated with muscle strength among dialysis patients. We aimed to test whether MIS is able to predict muscle strength in nondialysis-dependent chronic kidney disease (NDD-CKD) individuals. Design and Methods: This was a cross-sectional study conducted at the Dante Pazzanese Institute of Cardiology, Hypertension, and Nephrology Division outpatient clinic. We evaluated 190 patients with NDD-CKD stages 2-5 (median 59.5 {[}interquartile range 51.4-66.9] years; 64% men). MIS was calculated without computing dialysis vintage to the scoring. HGS was assessed in the dominant arm. Anthropometric, laboratory, and body composition parameters were recorded. Results: A strong negative correlation was found between HGS and MIS (r = -0.42; P <= .001) in univariate analysis. In multivariate regressions, adjustment for age, sex, diabetes, glomerular filtration rate, body cell mass, and C-reactive protein did not materially diminish these relationships. Conclusions: MIS shares strong links with objective measures of muscle strength in NDD-CKD patients. (C) 2013 by the National Kidney Foundation, Inc. All rights reserved. (AU)

FAPESP's process: 10/16593-2 - Association between traditional, novel and uremic related risk factors and morbidity/mortality (all-cause and cardiovascular) in chronic kidney disease patients
Grantee:Antonio Carlos Cordeiro Silva Júnior
Support Opportunities: Regular Research Grants