Synthesis of Extended Chromophores Derived From 5,5-Dimethyloxyluciferin by Barton-Kellogg Methodology

Autor(es)

Wuerfel, Hendryk ^[1] ; Ciscato, Luiz Francisco Monteiro Leite ^[2] ; Weiss, Dieter ^[1] ; Goerls, Helmar ^[3] ; Beckert, Rainer ^[1]

Afiliação do(s) autor(es)

^[1] Univ Jena, Inst Organ & Makromol Chem, D-07743 Jena - Germany

^[2] Univ Fed ABC, Ctr Ciencias Nat & Humanas, BR-09210170 Santo Andre, SP - Brazil

^[3] Univ Jena, Inst Anorgan & Analyt Chem, D-07743 Jena - Germany

• Tipo de documento: Artigo Científico
• Fonte: SYNTHESIS-STUTTGART; v. 46, n. 8, p. 1114-1120, APR 2014.
• Citações Web of Science: 0

Resumo

An approach to the synthesis of modified methyl ether-protected dimethyloxyluciferin derivatives is presented, focusing on the enlargement of the pi-system. This was achieved by introducing an alkene bridge at the 4-position of the thiazoline moiety to link the two chromophoric substructures. The resulting derivatives show strong absorbing properties over a wide range of the visible spectrum. Also, the fluorescence properties of these novel dimethyloxyluciferin derivatives are unique and might lead to new photophysical studies and bioanalytical applications. (AU)

• Processo FAPESP: 12/02428-5 - Peróxidos orgânicos cíclicos: síntese e mecanismo de redução
• Beneficiário: Luiz Francisco Monteiro Leite Ciscato
• Modalidade de apoio: Auxílio à Pesquisa - Regular