Overview of the taxonomy and of the major secondar... - BV FAPESP
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Overview of the taxonomy and of the major secondary metabolites and their biological activities related to human health of the Laurencia complex (Ceramiales, Rhodophyta) from Brazil

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Autor(es):
Fujii, Mutue T. [1] ; Cassano, Valeria ; Stein, Erika M. [2] ; Carvalho, Luciana R. [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Inst Bot, Nucl Pesquisa Ficol, BR-04301902 Sao Paulo - Brazil
[2] Univ Sao Paulo, Dept Bot, Programa Posgrad, BR-05508 Sao Paulo - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY; v. 21, n. 2, p. 268-282, MAR-APR 2011.
Citações Web of Science: 30
Resumo

In Brazil, the Laurencia complex is represented by twenty taxa: Laurencia s.s. with twelve species, Palisada with four species (including Chondrophycus furcatus now that the proposal of its transference to Palisada is in process), and Osmundea and Yuzurua with two species each. The majority of the Brazilian species of the Laurencia complex have been phylogenetically analyzed by 54 rbcL sequences, including five other Rhodomelacean species as outgroups. The analysis showed that the Laurencia complex is monophyletic with high posterior probability value. The complex was separated into five clades, corresponding to the genera: Chondrophycus, Laurencia, Osmundea, Palisada, and Yuzurua. A bibliographical survey of the terpenoids produced by Brazilian species showed that only six species of Laurencia and five of Palisada (including C. furcatcus) have been submitted to chemical analysis with 48 terpenoids (47 sesquiterpenes and one triterpene) isolated. No diterpenes were found. Of the total, 23 sesquiterpenes belong to the bisabolane class and eighteen to the chamigrene type, whose biochemical precursor is bisabolane, two are derived from lauranes and four are triquinols. Despite the considerable number of known terpenes and their ecological and pharmacological importance, few experimental biological studies have been performed. In this review, only bioactivities related to human health were considered. (AU)

Processo FAPESP: 08/07775-0 - Avaliação das atividades biológicas dos extratos de algas vermelhas do gênero Laurencia (Rhodomelaceae, Ceramiales)
Beneficiário:Erika Mattos Stein
Modalidade de apoio: Bolsas no Brasil - Mestrado
Processo FAPESP: 10/52244-2 - Diversidades e relações filogenéticas de algas marinhas bentônicas: o complexo Laurencia (Rhodophyta) no Atlântico Tropical e Subtropical
Beneficiário:Valéria Cassano
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 10/50193-1 - Estudos de bioprospecção de macroalgas marinhas, uso da biomassa algal como fonte de novos fármacos e bioativos economicamente viáveis e sua aplicação na remediação de áreas impactadas. (Biodiversidade marinha)
Beneficiário:Pio Colepicolo Neto
Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático