Physical and Chemical Properties and Subcutaneous Implantation of Mineral Trioxide Aggregate Mixed with Propylene Glycol

Autor(es)

Marciano, Marina Angelica ^[1] ; Guimaraes, Bruno Martini ^[1] ; Amoroso-Silva, Pablo ^[1] ; Camilleri, Josette ^[2] ; Hungaro Duarte, Marco Antonio ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Dent Sch Bauru, Dept Dent, BR-09500900 Sao Paulo - Brazil

^[2] Univ Malta, Fac Dent Surg, Dept Restorat Dent, Msida - Malta

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF ENDODONTICS; v. 42, n. 3, p. 474-479, MAR 2016.
• Citações Web of Science: 9

Resumo

Introduction: The aim of this study was to evaluate the physical, chemical, and biological properties of mineral trioxide aggregate (MTA) mixed with 80% distilled water and 20% propylene glycol (PG) compared with MTA mixed with distilled water only. Methods: Flowability, film thickness, and solubility were analyzed according to American National Standards Institute/American Dental Association specification 57/2000. Initial and final setting times were assessed according to American Society for Testing and Materials specification C266/08. Porosity was assessed by using mercury intrusion porosimetry after 1 and 28 days of hydration, and the pH and calcium ion release were assessed after 3, 24, 72, and 168 hours. For the tissue reaction, the cements were implanted in 24 albino rats (2 groups, n = 12). An analysis of the inflammatory infiltrate was performed after 15, 30, and 60 days. Results: MTA + PG exhibited lower film thickness and higher final setting time. No differences were verified for flowability (P > .05). MTA PG showed high porosity at 1 day of hydration (P < .05). All the test cements demonstrated an alkaline pH. Microscopic analysis of the specimens revealed neoformation of connective tissue in contact with the cements. Conclusions: The introduction of PG as a mixing vehicle alters the physical and chemical properties of MTA and is biologically acceptable. (AU)

• Processo FAPESP: 13/04054-8 - Análise da microestrutura e da interface de cimentos à base de silicato de cálcio contendo diferentes radiopacificadores
• Beneficiário: Marina Angélica Marciano da Silva
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
• Processo FAPESP: 14/01003-6 - Adição de cloreto de alumínio e fluoreto de alumínio para inibir a descoloração dentária ocasionada pelo MTA: avaliação das propriedades físicas, químicas e biológicas
• Beneficiário: Marina Angélica Marciano da Silva
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado