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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran Leptodactylus latinasus

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Autor(es):
Manuel Perez-Iglesias, Juan [1, 2] ; Franco-Belussi, Lilian [3] ; Moreno, Liliana [1] ; Tripole, Susana [1] ; de Oliveira, Classius [3] ; Sebastian Natale, Guillermo [1, 2]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Nacl San Luis, PROICO 9401, Area Zool, Fac Quim Bioquim & Farm, Chacabuco 917, RA-5700 San Luis - Argentina
[2] Univ Nacl La Plata, Fac Ciencias Exactas, Ctr Invest Medio Ambiente, CONICET, Dept Quim, RA-1900 La Plata, Buenos Aires - Argentina
[3] Sao Paulo State Univ, Dept Biol, IBILCE, UNESP, Rua Cristovao Colombo 2265, BR-15054000 Sao Jose Do Rio Preto, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: Environmental Science and Pollution Research; v. 23, n. 10, p. 9852-9861, MAY 2016.
Citações Web of Science: 16
Resumo

Glyphosate (GLY) is the most used herbicide worldwide and its effects on anurans are well known. Pollutants can cause physiological and morphological effects. Therefore, this study evaluated the effects of GLY on hepatic melanomacrophages as a response to environmental stressors. Three treatments were exposed to different concentrations of pure GLY (100, 1000, and 10,000 mu g g(-1), respectively), and there was also a control group. After the experimental time, liver and blood were analyzed. Melanomacrophages (MMCs) were located between the hepatocyte cordons, close to sinusoids. GLY increased the melanin area in MMCs of Leptodactylus latinasus exposed since lowest concentration until highest concentration. GLY also changed the occurrence of hepatic catabolism pigments into melanomacrophages and erythrocyte nuclear abnormalities; therefore, it can interfere with the hepatic metabolism. In conclusion, GLY promotes alterations in the hepatic tissue and erythrocyte nuclear abnormalities. Furthermore, MMCs may be useful as morphological responses of GLY effects. (AU)

Processo FAPESP: 14/00946-4 - Pigmentação visceral em animais ectotérmicos: imunidade inata e defesa contra UV
Beneficiário:Lilian Franco Belussi
Linha de fomento: Bolsas no Brasil - Pós-Doutorado
Processo FAPESP: 13/02067-5 - Efeitos tóxicos dos herbicidas Atrazina e Roundup em Eupemphix nattereri (Leiuperidae) e Rhinella schneideri (Bufonidae): alterações morfológicas sob diferentes concentrações e condições abióticas (pH, temperatura e fotoperíodo)
Beneficiário:Classius de Oliveira
Linha de fomento: Auxílio à Pesquisa - Regular