Anthropometric, functional capacity, and oxidative stress changes in Brazilian community-living elderly subjects. A longitudinal study

Autor(es)

Moreira, Priscila Lucelia ; Correa, Camila Renata ; Corrente, Jose Eduardo ; Martin, Luis Cuadrado ; Fortes Villas Boas, Paulo Jose ; Anjos Ferreira, Ana Lucia

• Tipo de documento: Artigo Científico
• Fonte: ARCHIVES OF GERONTOLOGY AND GERIATRICS; v. 66, p. 140-146, SEP-OCT 2016.
• Citações Web of Science: 4

Resumo

Objective: To examine the changes and relationships among anthropometric, functional and plasma oxidative stress markers in elderly. Design: longitudinal study. Setting: measurements in 2008 and 2010. Participants: 103 community-dwelling men and women aged 67-92. Measurements: Anthropometric parameters {[}waist, hip, arm and calf circumferences; waist-hip ratio, triceps skinfold thickness and others], basic (ADL) and instrumental activities of daily living (IADL)] and plasma oxidative stress markers (alpha-tocopherol, beta-carotene and malondialdehyde) were assessed in 2008 and 2010. Results: ADL, IADL, body weight, skinfold thickness and circumferences of calf and arm decreased and waist and waist-hip ratio increased from 2008 to 2010. alpha-Tocopherol decreased and malondialdehyde plasma levels increased during the study period. In multiple logistic regression analyses, increased age (OR = 1.12; IC: 1.02-1.23; p = 0.02), female gender (OR = 8.43; IC: 1.23-57.58; p = 0.03), hypertension (OR = 0.22; IC: 0.06-0.79; p = 0.02), arthritis/arthrosis (OR = 0.09; IC: 0.009-0.87; p = 0.04) and depression (OR = 0.20; IC: 0.04-1.03; p = 0.05) were independent risk factors for functional decline. Conclusion: Fat reduction, muscle loss, central obesity increase, functional decline and worsening of plasma oxidative stress were observed during 2-year follow-up. Some of the risk factors that were identified could be modified to help prevent functional decline in elderly. The factors deserving attention include hypertension, arthritis/arthrosis and depression. (C) 2016 Elsevier Ireland Ltd. All rights reserved. (AU)

• Processo FAPESP: 07/07455-2 - Avaliação evolutiva do estresse oxidativo cardíaco induzido pela doxorubicina em ratos: estudo do mecanismo de lesão
• Beneficiário: Ana Lucia do Anjos Ferreira
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 07/57545-8 - Avaliacao nutricional, da capacidade funcional e do estresse oxidativo de idosos da cidade de botucatu - sp.
• Beneficiário: Priscila Lucélia Moreira
• Modalidade de apoio: Bolsas no Brasil - Mestrado