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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Anthropometric, functional capacity, and oxidative stress changes in Brazilian community-living elderly subjects. A longitudinal study

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Author(s):
Moreira, Priscila Lucelia ; Correa, Camila Renata ; Corrente, Jose Eduardo ; Martin, Luis Cuadrado ; Fortes Villas Boas, Paulo Jose ; Anjos Ferreira, Ana Lucia
Total Authors: 6
Document type: Journal article
Source: ARCHIVES OF GERONTOLOGY AND GERIATRICS; v. 66, p. 140-146, SEP-OCT 2016.
Web of Science Citations: 4
Abstract

Objective: To examine the changes and relationships among anthropometric, functional and plasma oxidative stress markers in elderly. Design: longitudinal study. Setting: measurements in 2008 and 2010. Participants: 103 community-dwelling men and women aged 67-92. Measurements: Anthropometric parameters {[}waist, hip, arm and calf circumferences; waist-hip ratio, triceps skinfold thickness and others], basic (ADL) and instrumental activities of daily living (IADL)] and plasma oxidative stress markers (alpha-tocopherol, beta-carotene and malondialdehyde) were assessed in 2008 and 2010. Results: ADL, IADL, body weight, skinfold thickness and circumferences of calf and arm decreased and waist and waist-hip ratio increased from 2008 to 2010. alpha-Tocopherol decreased and malondialdehyde plasma levels increased during the study period. In multiple logistic regression analyses, increased age (OR = 1.12; IC: 1.02-1.23; p = 0.02), female gender (OR = 8.43; IC: 1.23-57.58; p = 0.03), hypertension (OR = 0.22; IC: 0.06-0.79; p = 0.02), arthritis/arthrosis (OR = 0.09; IC: 0.009-0.87; p = 0.04) and depression (OR = 0.20; IC: 0.04-1.03; p = 0.05) were independent risk factors for functional decline. Conclusion: Fat reduction, muscle loss, central obesity increase, functional decline and worsening of plasma oxidative stress were observed during 2-year follow-up. Some of the risk factors that were identified could be modified to help prevent functional decline in elderly. The factors deserving attention include hypertension, arthritis/arthrosis and depression. (C) 2016 Elsevier Ireland Ltd. All rights reserved. (AU)

FAPESP's process: 07/07455-2 - Time-course of oxidative stress induced by doxorubicin in rats: damage mechanism
Grantee:Ana Lucia do Anjos Ferreira
Support Opportunities: Regular Research Grants