The effect of seasons on Brazilian red propolis and its botanical source: chemical composition and antibacterial activity

Autor(es)

Bueno-Silva, Bruno ; Marsola, Alexandre ; Ikegaki, Masaharu ; Alencar, Severino M. ; Rosalen, Pedro L.

• Tipo de documento: Artigo Científico
• Fonte: NATURAL PRODUCT RESEARCH; v. 31, n. 11, p. 1318-1324, 2017.
• Citações Web of Science: 18

Resumo

The aim of this study was to evaluate the effect of seasons on the chemical composition and antibacterial activity of Brazilian red propolis (BRP) and its plant source. BRP was collected from Maceio, Alagoas state, north-east of Brazil, during one year. Chemical composition was determined by physicochemical analyses and HPLC while antimicrobial activity was assessed against Streptococcus mutans, Streptococcus sobrinus, Staphylococcus aureus and Actinomyces naeslundii by determining the minimal inhibitory and bactericidal concentrations (MIC and MBC, respectively). The comparative chemical profiles varied quantitatively according to the collection period. Formononetin was the most abundant compound in both propolis and resin, while isoliquiritigenin, (3S)-neovestitol, (3S)-vestitol are suggested to be responsible for antimicrobial activity of Brazilian red propolis. MIC varied from 15.6 to 125g/mL, whereas MBC varied from 31.2 to 500g/mL. Therefore, season in which propolis and its botanical source are collected indeed influences their chemical compositions, resulting in variations in their antibacterial activity. {[}GRAPHICS] (AU)

• Processo FAPESP: 04/08635-6 - Isolamento e identificação de compostos bioativos de uma nova variedade de própolis brasileira produzida por abelhas da espécie Apis mellifera
• Beneficiário: Severino Matias de Alencar
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 05/58199-0 - Analise de uma nova propolis em relacao a sua origem botanica, composicao quimica e atividade biologica.
• Beneficiário: Bruno Bueno Silva
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 06/55276-7 - Caracterizacao da propolis vermelha: sua origem botanica, composicao quimica e atividade biologica.
• Beneficiário: Pedro Luiz Rosalen
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 08/51048-5 - Avaliação do potencial antifúngico de própolis de Apis mellifera contra leveduras do gênero Candida
• Beneficiário: Marta Cristina Teixeira Duarte
• Modalidade de apoio: Auxílio à Pesquisa - Regular