Spread of multidrug-resistant high-risk Klebsiella pneumoniae clones in a tertiary hospital from southern Brazil

Autor(es)

Goncalves, Guilherme Bartolomeu ^[1] ; Rueda Furlan, Joao Pedro ^[1] ; Vespero, Eliana Carolina ^[2] ; Pelisson, Marsileni ^[2] ; Stehling, Eliana Guedes ^[1] ; Pitondo-Silva, Andre ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, Av Cafe S-N, BR-14040903 Ribeirao Preto, SP - Brazil

^[2] Univ Estadual Londrina, Dept Patol Anal Clin & Toxicol, Londrina, Parana - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INFECTION GENETICS AND EVOLUTION; v. 56, p. 1-7, DEC 2017.
• Citações Web of Science: 6

Resumo

Klebsiella pneumoniae is among the most important pathogens found in hospitals. The emergence of multiple antibiotic resistant K. pneumoniae associated with its virulence factors is a worldwide concern and its early identification is crucial, especially for controlling the spread of emerging clones. This article reports a high prevalence of multiresistant K. pneumoniae in a university hospital in southern Brazil, harboring several virulence and beta-lactamase encoding genes, including pandrug-resistant high-risk international clones belonging to the clonal group 258 (ST11, ST15, ST101, ST258, ST340 and ST874). (AU)

• Processo FAPESP: 13/22581-5 - Estudo dos mecanismos de patogenicidade e correlação com resistência a antimicrobianos de Klebsiella pneumoniae isoladas no Brasil e em países dos cinco continentes
• Beneficiário: André Pitondo da Silva
• Linha de fomento: Auxílio à Pesquisa - Apoio a Jovens Pesquisadores