| Texto completo | |
| Autor(es): |
Aguilar, Patricia V.
[1, 2, 3]
;
de Souza, William Marciel
[4]
;
Silvas, Jesus A.
[1, 2, 3]
;
Wood, Thomas
[5]
;
Widen, Steven
[5]
;
Fumagalli, Marcilio Jorge
[4]
;
Teixeira Nunes, Marcio Roberto
[6]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Texas Med Branch, Dept Pathol, 301 Univ Blvd, Galveston, TX 77555 - USA
[2] Inst Human Infect & Immun, Galveston, TX - USA
[3] Ctr Trop Dis, Galveston, TX - USA
[4] Univ Sao Paulo, Sch Med Ribeirao Preto, Virol Res Ctr, Sao Paulo - Brazil
[5] Univ Texas Med Branch, Dept Biochem & Mol Biol, Galveston, TX 77555 - USA
[6] Inst Evandro Chagas, Ctr Technol Innovat, Ananindeua, Para - Brazil
Número total de Afiliações: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | American Journal of Tropical Medicine and Hygiene; v. 99, n. 2, p. 451-457, 2018. |
| Citações Web of Science: | 1 |
| Resumo | |
Estero Real virus (ERV) was isolated in 1980 from Ornithodoros tadaridae ticks collected in El Estero Real, Sancti Spiritus, Cuba. Antigenic characterization of the isolate based on serological methods found a relationship with Abras and Zegla viruses and, consequently, the virus was classified taxonomically within the Patois serogroup. Given the fact that genetic characterization of Patois serogroup viruses has not yet been reported and that ERV is the only virus within the Patois serogroup isolated from ticks, we recently conducted nearly complete genome sequencing in an attempt to gain further insight into the genetic relationship of ERV with other Patois serogroup viruses and members of Peri-bunyaviridae family (Bunyavirales order). With the exception of ERV, our sequencing and phylogenetic studies revealed the close relationship of the Patois serogroup viruses to each other, forming a clear divergent clade from other members of the Orthobunyavirus genus (Peribunyaviridae family). Notably, our analysis also revealed that ERV forms a monophyletic clade that is closely related to species of the Orthonairovirus genus (Nairoviridae family) in all the genome segments. In light of these findings, we believe that the taxonomic classification of ERV should be revised. (AU) | |
| Processo FAPESP: | 17/13981-0 - Caracterização, genômica e diagnóstico de vírus com importância em saúde pública no Brasil por sequenciamento de alto desempenho |
| Beneficiário: | William Marciel de Souza |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |
| Processo FAPESP: | 16/01414-1 - Produção de peptídeos recombinantes virais antigênicos e desenvolvimento de métodos sorológicos para diagnóstico de infecções pelos vírus Chikungunya, Mayaro e Zika |
| Beneficiário: | Marcilio Jorge Fumagalli |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |
| Processo FAPESP: | 12/24150-9 - Pesquisa de vírus em roedores silvestres, mosquitos e carrapatos |
| Beneficiário: | William Marciel de Souza |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |