Thermal, mechanical and electrical stimuli in antinociceptive studies in standing horses: an update

Autor(es)

Gozalo-Marcilla, Miguel ^{[1, 2]} ; Loureiro Luna, Stelio Pacca ^[3] ; Gasthuys, Frank ^[4] ; Schauvliege, Stijn ^[4]

Afiliação do(s) autor(es)

^[1] Univ Edinburgh, Royal Dick Sch Vet Studies, Easter Bush Campus, Edinburgh EH25 9RG, Midlothian - Scotland

^[2] Univ Edinburgh, Roslin Inst, Easter Bush Campus, Edinburgh EH25 9RG, Midlothian - Scotland

^[3] Sao Paulo State Univ UNESP, Sch Vet Med & Anim Sci, Dept Surg & Anaesthesiol, Botucatu, SP - Brazil

^[4] Univ Ghent, Fac Vet Med, Dept Surg & Anaesthesia Domest Anim, Merelbeke - Belgium

• Tipo de documento: Artigo de Revisão
• Fonte: VETERINARY ANAESTHESIA AND ANALGESIA; v. 47, n. 1, p. 15-27, JAN 2020.
• Citações Web of Science: 0

Resumo

Objective To perform a literature review of the thermal and mechanical antinociceptive devices used in pharmacological studies in standing horses published after 2011 (2012-2019). To complete a full literature review about electrical stimulation used for evaluation in similar studies. Databases used PubMed, Google Scholar and Web of Science. Conclusions A high level of standardization has been reached in antinociceptive studies in standing horses using thermal and mechanical stimuli in most recent years. Commercially available testing devices to deliver thermal, mechanical and electrical stimuli, with observation of aversive responses to these stimuli, are reliable, sensitive and specific. For electrical stimulus testing, there is evidence that the resistance between the electrodes should be measured and should not exceed 3 k Omega to guarantee consistent and reproducible stimuli. The specific analysis of electromyographic activity after an electrical stimulus provides more detailed information about the neurons stimulated. (AU)

• Processo FAPESP: 17/01425-6 - Aplicação clínica de diferentes taxas de infusão de detomidina e metadona em cavalos em estação.
• Beneficiário: Miguel Gozalo Marcilla
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Pós-Doutorado
• Processo FAPESP: 14/00474-5 - Efeitos antinociceptivos e farmacocinética em equinos tratados com diferentes doses baixas de metadona e detomidina
• Beneficiário: Miguel Gozalo Marcilla
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado