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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Thermal, mechanical and electrical stimuli in antinociceptive studies in standing horses: an update

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Author(s):
Gozalo-Marcilla, Miguel [1, 2] ; Loureiro Luna, Stelio Pacca [3] ; Gasthuys, Frank [4] ; Schauvliege, Stijn [4]
Total Authors: 4
Affiliation:
[1] Univ Edinburgh, Royal Dick Sch Vet Studies, Easter Bush Campus, Edinburgh EH25 9RG, Midlothian - Scotland
[2] Univ Edinburgh, Roslin Inst, Easter Bush Campus, Edinburgh EH25 9RG, Midlothian - Scotland
[3] Sao Paulo State Univ UNESP, Sch Vet Med & Anim Sci, Dept Surg & Anaesthesiol, Botucatu, SP - Brazil
[4] Univ Ghent, Fac Vet Med, Dept Surg & Anaesthesia Domest Anim, Merelbeke - Belgium
Total Affiliations: 4
Document type: Review article
Source: VETERINARY ANAESTHESIA AND ANALGESIA; v. 47, n. 1, p. 15-27, JAN 2020.
Web of Science Citations: 0
Abstract

Objective To perform a literature review of the thermal and mechanical antinociceptive devices used in pharmacological studies in standing horses published after 2011 (2012-2019). To complete a full literature review about electrical stimulation used for evaluation in similar studies. Databases used PubMed, Google Scholar and Web of Science. Conclusions A high level of standardization has been reached in antinociceptive studies in standing horses using thermal and mechanical stimuli in most recent years. Commercially available testing devices to deliver thermal, mechanical and electrical stimuli, with observation of aversive responses to these stimuli, are reliable, sensitive and specific. For electrical stimulus testing, there is evidence that the resistance between the electrodes should be measured and should not exceed 3 k Omega to guarantee consistent and reproducible stimuli. The specific analysis of electromyographic activity after an electrical stimulus provides more detailed information about the neurons stimulated. (AU)

FAPESP's process: 17/01425-6 - Clinical application of different constant rate infusions of detomidine and methadone in standing horses
Grantee:Miguel Gozalo Marcilla
Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 14/00474-5 - Antinociceptive effects and farmacokinetics in horses treated with different low doses of methadone and detomidine
Grantee:Miguel Gozalo Marcilla
Support Opportunities: Scholarships in Brazil - Post-Doctoral