Development and Characterization of Electrospun Nanostructures Using Polyethylene Oxide: Potential Means for Incorporation of Bioactive Compounds

Autor(es):Mostrar menos -

Ramos, Sergiana dos P. ^[1] ; Giaconia, Michele A. ^[1] ; Do Marco, Jonas T. ^[1] ; Paiva, Robert da S. ^[2] ; De Rosso, Veridiana V. ^[1] ; Lemes, Ailton C. ^[3] ; Egea, Mariana B. ^[4] ; Assis, Marcelo ^[2] ; Mazzo, Tatiana M. ^[5] ; Longo, Elson ^[2] ; Braga, Anna R. C. ^{[1, 6]}

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo UNIFESP, Dept Biosci, Silva Jardim St, 136, Vila Mathias, BR-11015020 Santos, SP - Brazil

^[2] CDMF LIEC UFSCar, Chem Dept, POB 676, BR-13560970 Sao Carlos, SP - Brazil

^[3] Univ Fed Rio de Janeiro UFRJ, Technol Ctr, Sch Chem, Dept Biochem Engn, Av Athos da Silveira Ramos 149, BR-21941909 Rio De Janeiro - Brazil

^[4] Fed Inst Educ Sci & Technol Goiano, Campus Rio Verde, BR-75901970 Rio Verde - Brazil

^[5] Univ Fed Sao Paulo UNIFESP, Inst Marine Sci, POB 11070-100, BR-11015020 Santos, SP - Brazil

^[6] Univ Fed Sao Paulo UNIFESP, Dept Chem Engn, Campus Diadema, BR-09972270 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: COLLOIDS AND INTERFACES; v. 4, n. 2 JUN 2020.
• Citações Web of Science: 0

Resumo

The development of processes for stabilization of the properties of bioactive compounds has been studied in recent years, and the use of nanotechnology is among the most discussed routes. The present work addressed the assembly of nanostructures using polyethylene oxide (PEO), the production of core-shell nanofibers (NFs) with bioactive compounds, and the evaluation of their microscopic and physical characteristics. Aqueous solutions of PEO were electrospun by varying different process and solution parameters (PEO and NaCl concentrations, feeding rate, the tip-to-collector distance (TCD), and applied voltage) in order to optimize production of nanostructures. The best condition obtained was evaluated to form core-shell NFs composed by jussara pulp as a source of anthocyanins. To assess the production of NFs with PEO and jussara pulp, feed solutions were prepared in acetate buffer (pH 4.5) with 6% PEO and 10% lyophilized jussara pulp, at a feeding rate of 150 mu L center dot h(-1)and TCD of 15 cm using an applied voltage of 10 kV to form core-shell NFs. The results revealed the formation of core-shell NFs with a diameter of 126.5 +/- 50.0 nm. The outcomes achieved represent a crucial step in the application of anthocyanins in food systems as pigments, establishing a basis for further research on the incorporation of nanomaterials into foodstuff. (AU)

• Processo FAPESP: 19/08975-7 - EMU concedido no processo 2018/15539-6: reômetro modular compacto e acessórios
• Beneficiário: Fabiana Perrechil Bonsanto
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários
• Processo FAPESP: 18/01550-8 - Nanoestruturas contendo antocianinas extraídas de juçara (Euterpe edulis Mart.): interação com bactérias ácido-láticas e biodisponibilidade
• Beneficiário: Anna Rafaela Cavalcante Braga
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/07296-2 - CDMF - Centro de Desenvolvimento de Materiais Funcionais
• Beneficiário: Elson Longo da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Processo FAPESP: 18/13408-1 - EMU concedido no processo 2018/01550-8: equipamento electro-spray para obtenção de compostos bioativos em nanoestruturas
• Beneficiário: Anna Rafaela Cavalcante Braga
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários