Protection and targeted delivery of beta-carotene by starch-alginate-gelatin emulsion-filled hydrogels

Autor(es)

Guedes Silva, Karen Cristina ^[1] ; Feltre, Gabriela ^[1] ; Hubinger, Miriam Dupas ^[1] ; Kawazoe Sato, Ana Carla ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Sch Food Engn, Dept Food Engn, Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Food Engineering; v. 290, FEB 2021.
• Citações Web of Science: 17

Resumo

Encapsulation systems present the potential to protect bioactive compounds and may promote targeted delivery to the gastrointestinal tract. In this study, beta-carotene was incorporated into emulsion-filled hydrogels composed of alginate, gelatin, and starch (native and gelatinized). The oxidative stability of encapsulated and free oil and the stability of beta-carotene were tested under accelerated storage conditions (65 degrees C for 6 days). The impact of in vitro digestibility on the morphology and microstructure of microgels was also evaluated and correlated with beta-carotene stability. The results indicate that encapsulation reduced oil oxidation and improved beta-carotene stability, compared with free oil with beta-carotene, highlighting the potential of starch-based microparticles to increase the shelf life of beta-carotene. Regarding the digestibility assay, both microparticles were resistant to simulated oral and stomach fluids. However, native starch-filled empty spaces of the biopolymer network protected the bioactive from the action of oxygen, acidity, pro-oxidants, and free radicals, consequently ensuring greater beta-carotene stability in the digesta. (AU)

• Processo FAPESP: 09/54137-1 - EMUS: aquisição de um analisador de distribuição de tamanho de partículas, um medidor de potencial zeta, um spray dryer e um sistema de cromatografia líquida de ultra alta pressão / espectrômetro de massa
• Beneficiário: Miriam Dupas Hubinger
• Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários
• Processo FAPESP: 07/58017-5 - Micro e nano emulsoes alimenticias: estudo reo-optico e de estabilidade.
• Beneficiário: Rosiane Lopes da Cunha
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 09/50593-2 - Concentração de extratos aquosos de própolis por nanofiltração
• Beneficiário: Miriam Dupas Hubinger
• Modalidade de apoio: Auxílio à Pesquisa - Regular