Microencapsulated and uncoated butyric acid as alternative additives to the regeneration of intestinal mucosa in broilers challenged with Eimeria spp.

Autor(es)

Ventura, G. ^[1] ; Lima, G. A. ^[1] ; Barbosa, B. F. S. ^[1] ; Polycarpo, G. V. ^[1] ; Denadai, J. C. ^[2] ; Costa, V. E. ^[2] ; Madeira, A. M. B. N. ^[3] ; Malheiros, R. D. ^[4] ; Cruz-Polycarpo, V. C. ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ Unesp, Coll Technol & Agr Sci, Rod Cmte, Joao Ribeiro Barros Km 651, BR-17900000 Dracena - Brazil

^[2] Sao Paulo State Univ Unesp, Stable Isotopes Ctr, Inst Biosci, Botucatu, SP - Brazil

^[3] Univ Sao Paulo, Inst Biomed Sci, Dept Parasitol, Sao Paulo - Brazil

^[4] North Carolina State Univ, Prestage Dept Poultry Sci, Raleigh, NC - USA

• Tipo de documento: Artigo Científico
• Fonte: BRITISH POULTRY SCIENCE; v. 62, n. 5, p. 717-725, SEP 3 2021.
• Citações Web of Science: 0

Resumo

1. The effect of microencapsulated and uncoated butyric acid as an alternative to antibiotics on performance, intestinal morphology and regeneration of intestinal mucosa was studied in birds experimentally infected with Eimeria spp. 1 to 42 d-old. 2. A total of 1,320 male Cobb (R) broiler chicks were allocated to one of five treatments in a completely randomised design, comprising a negative control, uncoated butyric acid (UA), microencapsulated butyric acid (MA), combined U + M butyric acid and a positive control (antibiotic+anticoccidial) in six replications. At 16 d-old, the birds were inoculated orally with 0.5 ml of a solution containing an Eimeria spp. pool. 3. At 21 d of age, the birds receiving butyric acid alone had higher body weight gain (BWG) and feed intake (FI) compared to those supplemented with the blend of acids. For the total rearing period, in all variables, the positive control performed best (P < 0.001). 4. At 14 d of age, birds that received diets containing UA had a deeper crypt depth in the jejunum than those fed diets containing microencapsulated acid (P = 0.0194). At 21 d of age, the birds fed the acids had higher villi (P = 0.0058) in the duodenum, compared to the negative control group. 5. Supplementation with microencapsulated acid contributed to the intestinal health and recovery of post-challenge birds, but did not result in improvements in performance. (AU)

• Processo FAPESP: 18/22986-9 - Efeito do ácido butírico livre e microencapsulado na dieta de frangos de corte desafiados com Eimeria spp. na contagem de células caliciformes intestinais
• Beneficiário: Gabriela Ventura
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Mestrado
• Processo FAPESP: 17/11745-8 - Ácido butírico livre e protegido em alternativa aos antibióticos em dietas para frangos de corte desafiados com Eimeria spp.
• Beneficiário: Gabriela Ventura
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 18/21792-6 - Butirato de sódio microencapsulado em dietas para frangos de corte desafiados com Eimeria spp.
• Beneficiário: Valquíria Cação Cruz-Polycarpo
• Modalidade de apoio: Auxílio à Pesquisa - Regular