"I put it in my head that the supplement would help me": Open-placebo improves exercise performance in female cyclists

Autor(es)

Saunders, Bryan ; Saito, Tiemi ; Klosterhoff, Rafael ; de Oliveira, Luana Farias ; Barreto, Gabriel ; Perim, Pedro ; Pinto, Ana Jessica ; Lima, Fernanda ; de Sapinto, Ana Lucia ; Gualano, Bruno

• Tipo de documento: Artigo Científico
• Fonte: PLoS One; v. 14, n. 9, p. 16-pg., 2019-09-24.

Resumo

This study investigated the effect of open-placebo on cycling time-trial (TT) performance. Twenty-eight trained female cyclists completed a 1-km cycling TT following a control session or an open-placebo intervention. The intervention consisted of an individual presentation, provided by a medic, in which the concept of open-placebo was explained to the participant, before she ingested two red and white capsules containing flour; 15 min later, they performed the TT. In the control session, the participant sat quietly for 20 min. Heart rate and ratings of perceived exertion (RPE) were monitored throughout exercise, while blood lactate was determined pre- and post-exercise. Post-exercise questionnaires were employed to gain insight into the perceived influence of the supplement on performance. Open-placebo improved time-to-completion (P = 0.039, 103.6 +/- 5.0 vs. 104.4 +/- 5.1 s, -0.7 +/- 1.8 s, -0.7 +/- 1.7%) and mean power output (P = 0.01, 244.8 +/- 34.7 vs. 239.7 +/- 33.2, +5.1 +/- 9.5 W) during the TT. Individual data analysis showed that 11 individuals improved, 13 remained unchanged and 4 worsened their performance with open-placebo. Heart rate, RPE and blood lactate were not different between sessions (all P>0.05). Positive expectation did not appear necessary to induce performance improvements, suggesting unconscious processes occurred, although a lack of an improvement appeared to be associated with a lack of belief. Open-placebo improved 1-km cycling TT performance in trained female cyclists. Although the intervention was successful for some individuals, individual variation was high, and some athletes did not respond or even performed worse. Thus, open-placebo interventions should be carefully considered by coaches and practitioners, while further studies are warranted. (AU)

• Processo FAPESP: 17/15314-1 - A influência do polimorfismo CYP1A2 sobre as respostas fisiológicas e de desempenho após a suplementação aguda de cafeína
• Beneficiário: Gabriel Henrique Castanho Barreto
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 16/50438-0 - Suplementação nutricional e exercício para otimizar o desempenho: foco nas respostas individuais e um passo para a nutrição esportiva personalizada
• Beneficiário: Bryan Saunders
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 15/26937-4 - Estudos sobre (in)atividade física em pacientes com artrite reumatóide: caracterização, associações com a doença e efeitos da interrupção do tempo sedentário
• Beneficiário: Ana Jéssica Pinto
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 17/04973-4 - Suplementação nutricional e exercício para otimizar o desempenho: foco nas respostas individuais e um passo para a nutrição esportiva personalizada
• Beneficiário: Bryan Saunders
• Modalidade de apoio: Bolsas no Brasil - Jovens Pesquisadores
• Processo FAPESP: 18/01594-5 - Respostas sanguíneas e musculares à suplementação de bicarbonato de sódio e subsequente desempenho do exercício
• Beneficiário: Pedro Henrique Lopes Perim
• Modalidade de apoio: Bolsas no Brasil - Mestrado