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Spinning gold: Unraveling the bioaccessibility and bioavailability of Pitanga's carotenoid microfibers

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Autor(es):
Neves, Bruna Vitoria ; Ramos, Sergiana dos Passos ; da Trindade, Leticia Guerreiro ; Nass, Pricila ; Jacob-Lopes, Eduardo ; Zepka, Leila Queiroz ; Braga, Anna Rafaela Cavalcante ; de Rosso, Veridiana Vera
Número total de Autores: 8
Tipo de documento: Artigo Científico
Fonte: Food Research International; v. 196, p. 11-pg., 2024-09-20.
Resumo

The design and development of nanoparticle- and microparticle-based delivery systems incorporating carotenoids into carrier materials offers multiple advantages, including enhancing the bio-efficacy of these compounds due to improving their bioaccessibility and bioavailability. This study introduced pitanga saponified carotenoid extract (PSCE) and pitanga non-saponified carotenoid extract (PSCE) in a 12 % zein/1 %PEO solution and electrospun for fiber production. Then, the fibers were characterized, and their bioaccessibility and bioavailability were also evaluated. The average mean diameter of carotenoid non-saponified microfiber (CNSM) and saponified (CSM) was 5.76 +/- 1.7 mu m and 4.92 +/- 1.4 mu m, respectively, indicating that the saponification process reduces the viscosity of the solution resulting in the development of finer microfibers. Carotenoid encapsulation efficiency ranged between 10.3 % and 8.43 % for saponified and non-saponified extracts, respectively. Surprisingly, no carotenoid release was detected from both microfibers after 72 h. Carotenoid bioaccessibility was higher in pitanga pulp compared to both microfibers. The xanthophylls showed higher bioavailability in pitanga pulp. The study's results suggest that the microfibers' structure significantly influenced carotenoid release and cellular absorption more than the chemical structure of carotenoids themselves. (AU)

Processo FAPESP: 18/13408-1 - EMU concedido no processo 2018/01550-8: equipamento electro-spray para obtenção de compostos bioativos em nanoestruturas
Beneficiário:Anna Rafaela Cavalcante Braga
Modalidade de apoio: Auxílio à Pesquisa - Programa Equipamentos Multiusuários
Processo FAPESP: 21/02692-3 - Estudo para substituição de corantes artificiais por carotenoides de frutas brasileiras: respostas tecnológicas inovadoras para aplicações em alimentos
Beneficiário:Veridiana Vera de Rosso
Modalidade de apoio: Auxílio à Pesquisa - Regular