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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Does creatine supplementation improve the plasma lipid profile in healthy male subjects undergoing aerobic training?

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Autor(es):
Gualano, Bruno [1, 2] ; Ugrinowitsch, Carlos [1] ; Artioli, Guilherme G. [1] ; Benatti, Fabiana B. [1] ; Scagliusi, Fernanda B. [1] ; Harris, Roger C. [3] ; Lancha Junior, Antonio H. [1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Phys Educ & Sport, Lab Appl Nutr & Metab, BR-05508 Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Med, Div Rheumatol, Lab Rheumatol Assessment & Conditioning, BR-05508 Sao Paulo - Brazil
[3] Univ Chichester, Sch Sport Exercise & Hlth Sci, Chichester, W Sussex - England
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION; v. 5, OCT 3 2008.
Citações Web of Science: 5
Resumo

We aimed to investigate the effects of creatine (Cr) supplementation on the plasma lipid profile in sedentary male subjects undergoing aerobic training. Methods: Subjects (n = 22) were randomly divided into two groups and were allocated to receive treatment with either creatine monohydrate (CR) (similar to 20 g.day(-1) for one week followed by similar to 10 g.day(-1) for a further eleven weeks) or placebo (PL) ( dextrose) in a double blind fashion. All subjects undertook moderate intensity aerobic training during three 40-minute sessions per week, over 3 months. High-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), very low-density lipoprotein cholesterol (VLDL), total cholesterol (TC), triglyceride (TAG), fasting insulin and fasting glycemia were analyzed in plasma. Thereafter, the homeostasis model assessment (HOMA) was calculated. Tests were performed at baseline (Pre) and after four (Post 4), eight (Post 8) and twelve (Post 12) weeks. Results: We observed main time effects in both groups for HDL (Post 4 versus Post 8; P = 0.01), TAG and VLDL (Pre versus Post 4 and Post 8; P = 0.02 and P = 0.01, respectively). However, no between group differences were noted in HDL, LDL, CT, VLDL and TAG. Additionally, fasting insulin, fasting glycemia and HOMA did not change significantly. Conclusion: These findings suggest that Cr supplementation does not exert any additional effect on the improvement in the plasma lipid profile than aerobic training alone. (AU)

Processo FAPESP: 03/14088-5 - Efeitos da suplementacao oral da creatina no perfil lipidico e tolerancia a glicose em homens nao treinados.
Beneficiário:Bruno Gualano
Modalidade de apoio: Bolsas no Brasil - Iniciação Científica