Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The Effects of Physical Exercise on the Serum Iron Profile in Spontaneously Hypertensive Rats

Texto completo
Autor(es):
Frank, Miriam K. [1] ; Esteves, Andrea Maculano [1] ; Lopes, Cleide [1] ; Cavagnolli, Daniel A. [1] ; Tufik, Sergio [1] ; de Mello, Marco Tulio [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Fed Sao Paulo, Dept Psicobiol, Sao Paulo - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: BIOLOGICAL TRACE ELEMENT RESEARCH; v. 145, n. 2, p. 222-224, FEB 2012.
Citações Web of Science: 1
Resumo

The purpose of this study was to evaluate the profile of serum iron in spontaneously hypertensive rats after an aerobic physical exercise. To accomplish this, 12 normotensive Wistar rats and 12 spontaneously hypertensive rats were distributed into ``physical exercise{''} and ``no physical exercise{''} groups. The animals in the physical exercise group underwent to an aerobic exercise for a total of 4 weeks. Blood was collected for the analysis of iron. Our results indicate that rats of the physical exercise group had significantly lower serum iron levels after the aerobic exercise protocol compared to the spontaneously hypertensive rats no physical exercise group (F ((3,16)) = 4.4915, p < 0.01). No significant difference was found between no physical exercise groups. The results indicated that the difference in iron may be due to an increased demand for iron, prompted by chronic physical exercise. In addition, erythrocytosis has been associated with increased blood pressure in spontaneously hypertensive rats, suggesting that iron reduction may be related to decreased blood pressure in these animals. (AU)

Processo FAPESP: 98/14303-3 - Center for Sleep Studies
Beneficiário:Sergio Tufik
Linha de fomento: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
Processo FAPESP: 08/50646-6 - Efeitos do exercício físico em um modelo animal de síndrome das pernas inquietas e de movimentos periódicos das pernas
Beneficiário:Andrea Maculano Esteves
Linha de fomento: Bolsas no Brasil - Pós-Doutorado