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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Effects of Physical Exercise on the Serum Iron Profile in Spontaneously Hypertensive Rats

Full text
Author(s):
Frank, Miriam K. [1] ; Esteves, Andrea Maculano [1] ; Lopes, Cleide [1] ; Cavagnolli, Daniel A. [1] ; Tufik, Sergio [1] ; de Mello, Marco Tulio [1]
Total Authors: 6
Affiliation:
[1] Univ Fed Sao Paulo, Dept Psicobiol, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: BIOLOGICAL TRACE ELEMENT RESEARCH; v. 145, n. 2, p. 222-224, FEB 2012.
Web of Science Citations: 1
Abstract

The purpose of this study was to evaluate the profile of serum iron in spontaneously hypertensive rats after an aerobic physical exercise. To accomplish this, 12 normotensive Wistar rats and 12 spontaneously hypertensive rats were distributed into ``physical exercise{''} and ``no physical exercise{''} groups. The animals in the physical exercise group underwent to an aerobic exercise for a total of 4 weeks. Blood was collected for the analysis of iron. Our results indicate that rats of the physical exercise group had significantly lower serum iron levels after the aerobic exercise protocol compared to the spontaneously hypertensive rats no physical exercise group (F ((3,16)) = 4.4915, p < 0.01). No significant difference was found between no physical exercise groups. The results indicated that the difference in iron may be due to an increased demand for iron, prompted by chronic physical exercise. In addition, erythrocytosis has been associated with increased blood pressure in spontaneously hypertensive rats, suggesting that iron reduction may be related to decreased blood pressure in these animals. (AU)

FAPESP's process: 98/14303-3 - Center for Sleep Studies
Grantee:Sergio Tufik
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC