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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Global ITS diversity in the Sporothrix schenckii complex

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Autor(es):
Zhou, Xun [1, 2] ; Rodrigues, Anderson M. [1, 3] ; Feng, Peiying [1, 4] ; de Hoog, G. S. [5, 1, 6, 7]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Cent Bur Schimmelcultures KNAW Fungal Biodiervs C, NL-3508 AD Utrecht - Netherlands
[2] Chongqing Med Univ, Dept Dermatol, Affiliated Hosp, Chongqing - Peoples R China
[3] Fed Univ Sao Paulo UNIFESP, Cellular Biol Div, DMIP, Sao Paulo - Brazil
[4] Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510275, Guangdong - Peoples R China
[5] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, Amsterdam - Netherlands
[6] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou 510275, Guangdong - Peoples R China
[7] Peking Univ, Hlth Sci Ctr, Res Ctr Med Mycol, Beijing 100871 - Peoples R China
Número total de Afiliações: 7
Tipo de documento: Artigo Científico
Fonte: FUNGAL DIVERSITY; v. 66, n. 1, p. 153-165, MAY 2014.
Citações Web of Science: 44
Resumo

Molecular phylogeny has revealed that sporotrichosis is caused by several Sporothrix species which differ in clinical behavior. The complex is embedded within Ophiostoma, a genus mainly comprising fungi that live in association with bark beetles, but differs by a high virulence towards humans and other mammals. The different ecology is corroborated by phylogenetic separation. The aim of the present study was to determine the validity of the rDNA internal transcribed spacer (ITS) region as a marker for diagnostics of species in the clinical group, using beta-tubulin sequences to calibrate species delimitations. The topology of the two gene trees was concordant, and all clinically relevant Sporothrix species could easily be recognized by means of the ITS region. An increased geographic sampling did not affected delimitation success in the clinical clade of the S. schenckii complex. (AU)

Processo FAPESP: 11/07350-1 - Biologia do complexo Sporothrix schenckii: Análise de marcadores moleculares e proteômicos e o papel de moléculas antigênicas e antifúngicas na esporotricose
Beneficiário:Anderson Messias Rodrigues
Modalidade de apoio: Bolsas no Brasil - Doutorado