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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Global ITS diversity in the Sporothrix schenckii complex

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Author(s):
Zhou, Xun [1, 2] ; Rodrigues, Anderson M. [1, 3] ; Feng, Peiying [1, 4] ; de Hoog, G. S. [5, 1, 6, 7]
Total Authors: 4
Affiliation:
[1] Cent Bur Schimmelcultures KNAW Fungal Biodiervs C, NL-3508 AD Utrecht - Netherlands
[2] Chongqing Med Univ, Dept Dermatol, Affiliated Hosp, Chongqing - Peoples R China
[3] Fed Univ Sao Paulo UNIFESP, Cellular Biol Div, DMIP, Sao Paulo - Brazil
[4] Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510275, Guangdong - Peoples R China
[5] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, Amsterdam - Netherlands
[6] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou 510275, Guangdong - Peoples R China
[7] Peking Univ, Hlth Sci Ctr, Res Ctr Med Mycol, Beijing 100871 - Peoples R China
Total Affiliations: 7
Document type: Journal article
Source: FUNGAL DIVERSITY; v. 66, n. 1, p. 153-165, MAY 2014.
Web of Science Citations: 44
Abstract

Molecular phylogeny has revealed that sporotrichosis is caused by several Sporothrix species which differ in clinical behavior. The complex is embedded within Ophiostoma, a genus mainly comprising fungi that live in association with bark beetles, but differs by a high virulence towards humans and other mammals. The different ecology is corroborated by phylogenetic separation. The aim of the present study was to determine the validity of the rDNA internal transcribed spacer (ITS) region as a marker for diagnostics of species in the clinical group, using beta-tubulin sequences to calibrate species delimitations. The topology of the two gene trees was concordant, and all clinically relevant Sporothrix species could easily be recognized by means of the ITS region. An increased geographic sampling did not affected delimitation success in the clinical clade of the S. schenckii complex. (AU)

FAPESP's process: 11/07350-1 - Biology of Sporothrix schenckii complex: Analysis of molecular and proteomics markers, and the role of antigenic and antifungal molecules in sporotrichosis
Grantee:Anderson Messias Rodrigues
Support Opportunities: Scholarships in Brazil - Doctorate