Small calcified lesions suggestive of neurocysticercosis are associated with mesial temporal sclerosis

Autor(es)

Oliveira, Marcos C. B. ^[1] ; Martin, Maria G. M. ^[2] ; Tsunemi, Miriam H. ^[3] ; Vieira, Gilson ^[4] ; Castro, Luiz H. M. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Med, Dept Neurol, Sao Paulo - Brazil

^[2] Fac Med Sao Paulo, Hosp Clin, Inst Radiol, Lab Invest Med 44, Sao Paulo - Brazil

^[3] Univ Estadual Paulista Julio de Mesquite Fitho, Inst Biociencias, Dept Bioestatist, Botucatu, SP - Brazil

^[4] Fac Med Sao Paulo, Hosp Clin, Inst Radiol, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Arquivos de Neuro-Psiquiatria; v. 72, n. 7, p. 510-516, JUL 2014.
• Citações Web of Science: 9

Resumo

Recent studies have suggested a possible relationship between temporal lobe epilepsy with mesial temporal sclerosis (MTS) and neurocysticercosis (NC). We performed a case-control study to evaluate the association of NC and MTS. Method: : We randomly selected patients with different epilepsy types, including: MTS, primary generalized epilepsy (PGE) and focal symptomatic epilepsy (FSE). Patients underwent a structured interview, followed by head computed tomography (CT). A neuroradiologist evaluated the scan for presence of calcified lesions suggestive of NC. CT results were matched with patients' data. Results: : More patients in the MTS group displayed calcified lesions suggestive of NC than patients in the other groups (p=0.002). On multivariate analysis, MTS was found to be an independent predictor of one or more calcified NC lesions (p=0.033). Conclusion: : After controlling for confounding factors, we found an independent association between NC calcified lesions and MTS. (AU)

• Processo FAPESP: 08/04119-4 - Neurocisticercose com lesões calcificadas e epilepsia mesial temporal com esclerose de hipocampo. Associação fortuita ou possível papel etiológico?
• Beneficiário: Marcos Castello Barbosa de Oliveira
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 05/56464-9 - Centro de Imagem em Neurociências da Faculdade de Medicina da Universidade de São Paulo
• Beneficiário: Giovanni Guido Cerri
• Modalidade de apoio: Auxílio à Pesquisa - Programa CINAPCE - Temático