Small calcified lesions suggestive of neurocysticercosis are associated with mesial temporal sclerosis

Author(s)

Oliveira, Marcos C. B. ^[1] ; Martin, Maria G. M. ^[2] ; Tsunemi, Miriam H. ^[3] ; Vieira, Gilson ^[4] ; Castro, Luiz H. M. ^[1]

Affiliation

^[1] Univ Sao Paulo, Fac Med, Dept Neurol, Sao Paulo - Brazil

^[2] Fac Med Sao Paulo, Hosp Clin, Inst Radiol, Lab Invest Med 44, Sao Paulo - Brazil

^[3] Univ Estadual Paulista Julio de Mesquite Fitho, Inst Biociencias, Dept Bioestatist, Botucatu, SP - Brazil

^[4] Fac Med Sao Paulo, Hosp Clin, Inst Radiol, Sao Paulo - Brazil

• Document type: Journal article
• Source: Arquivos de Neuro-Psiquiatria; v. 72, n. 7, p. 510-516, JUL 2014.
• Web of Science Citations: 9

Abstract

Recent studies have suggested a possible relationship between temporal lobe epilepsy with mesial temporal sclerosis (MTS) and neurocysticercosis (NC). We performed a case-control study to evaluate the association of NC and MTS. Method: : We randomly selected patients with different epilepsy types, including: MTS, primary generalized epilepsy (PGE) and focal symptomatic epilepsy (FSE). Patients underwent a structured interview, followed by head computed tomography (CT). A neuroradiologist evaluated the scan for presence of calcified lesions suggestive of NC. CT results were matched with patients' data. Results: : More patients in the MTS group displayed calcified lesions suggestive of NC than patients in the other groups (p=0.002). On multivariate analysis, MTS was found to be an independent predictor of one or more calcified NC lesions (p=0.033). Conclusion: : After controlling for confounding factors, we found an independent association between NC calcified lesions and MTS. (AU)

• FAPESP's process: 08/04119-4 - Neurocysticercosis with calcified lesions and mesial temporal epilepsy associated with hipocampal sclerosis: fortuitus association or a possible etiologic role?
• Grantee: Marcos Castello Barbosa de Oliveira
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 05/56464-9 - Neuroscience Imaging Center at University of São Paulo Medical School
• Grantee: Giovanni Guido Cerri
• Support Opportunities: Inter-institutional Cooperation in Support of Brain Research (CINAPCE) - Thematic Grants