French National Institute of Health and Medical Research (INSERM)

• Human genetics in mycobacterial infections: new molecular genetic defects involved in Mendelian susceptibility to mycobacterial infections, AP.R

• Abstract

  IgA Nephropathy (IgAN), the major primary glomerulonephritis (GN) worldwide, is characterized by the mesangial deposition of IgA1-containing complexes (Monteiro et al., 2002). This apparently benign condition was revealed to be a major health problem due to the fact that around 25 to 40% of patients progress to end-stage renal disease following 20 years of disease onset (Coppo and D'Amico…

  Cellular consequences of mesangial IgA deposition in IgA nephropathy, AP.R

• Abstract

  There is evidence that nitric oxide plays a role in the neurotransmitter balance within the basal ganglia and in the pathology of Parkinson's disease (PD). Treatment with the L-NOARG reduced 6-OHDA-induced dopaminergic damage in the dorsal striatum, ventral substantia nigra and lateral globus pallidus. L-NOARG reduced 6-OHDA-induced striatal increase, and substantia nigra compacta decreas…

  Analysis of nitric oxide synthase in dopaminergic and non dopaminergic neurons in experimental Parkinson Disease: role of NOS inhibitors in L-DOPA induced diskinesias, AP.R

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