FAPESP Innovative Research in Small Business (PIPE) aims to support scientific and technological research, carried out in startups and small innovative companies in the State of São Paulo. The projects are carried out under the responsibility of investigators who have an employment contract with those companies or are associated with them for research development. The selection is through a peer-reviewing system. Phase 1 is used to verify the technical and scientific feasibility of the proposal, lasting up to 9 months.
Companies' research projects supported by PIPE Program
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The project proposes the development of an innovative hybrid route for the production of fungal bioinputs, using the production of Trichoderma asperellum spores as a model and integrating submerged fermentation (SmF) and solid-state fermentation (SSF). Cultivation in a homogeneous liquid medium enables rapid mycelial growth, high yield, and process standardization, with lower batch-to-bat…
With 22,773 new diagnoses in 2023, Brazil is the second-highest country in terms of confirmed instances of leprosy, a socially determined illness, after India. The goal of this research is to create a serological test for leprosy diagnosis and evaluate its technological viability. The objective is to develop a test that can swiftly and accurately diagnose the illness while remaining finan…
Currently, all messages regarding questions from researchers funded by FAPESP go to email, and after being answered, no record is generated for later consultation or generation of records totaling responses and demand notes.The Project consists of creating a "Contact Us" Service System, where responses will be stored in a database with "Questions and Answers," forming a knowledge base for…
This project proposes to create an intelligent platform that combines data science, personalized communication, and decision support to increase adherence to the surgical journey of ophthalmologic diseases. It is estimated that thousands of patients abandon the surgical process due to logistical and emotional difficulties or lack of support from family members and caregivers. Although the…
Reasons, Causes, and Problems:When an aircraft flies through a cloud of supercooled droplets, they impact exposed surfaces and can either freeze immediately due to a metastable condition, forming "rime" ice, or impact and then freeze later due to convection, forming "glaze" ice.Ice formation can cause: lift degradation, weight increase, drag increase, ice ingestion by engines, ice on prop…
The convergence of educational technology, data science, and artificial intelligence has driven innovative methodologies for assessing competencies in digital contexts. The field of learning analytics has established itself as a central approach to understanding learning patterns, with significant advances in frameworks such as learning analytics for Learning and Growth Design and the Eur…
(Only some records are available in English at this moment)
In animal production, differential performance between males and females occurs. In the yellowtail tetra Astyanax altiparanae, females (XX) are larger and presents better growth performance than males (XY). This differential growth generates heterogeneity in weight and size during grow-out phase, which is not adequate for the fish processing industry. Therefore, the production of monosex …
Property inspections play a crucial role in accurately assessing the value and condition of a property before any commercial transaction, whether for sale, rental, handover of a new property, or even for short-term rentals. By ensuring the integrity of the property and identifying potential defects, inspections provide security and peace of mind to all parties involved, including owners, …
Current methods for manufacturing surfboards are inefficient in terms of sustainability due to waste generation, low utilization of base materials, and limited mechanical strength, as surfboards lack an adequate internal structure. Additionally, the choice of more fragile, petroleum-derived materials exacerbates the issue. These factors raise global concerns due to their negative environm…
(Only some records are available in English at this moment)
A divulgação de dados relacionados às emissões de Gases de Efeito Estufa (GEE), embora ainda não seja obrigatória em âmbito nacional, tem se tornado cada vez mais comum, impulsionada principalmente por compromissos voluntários com boas práticas ambientais. A complexidade envolvida na quantificação das emissões totais de uma empresa - considerando toda a sua cadeia de produção, manufatura …
O projeto consiste no desenvolvimento de uma solução completa que inicia pela criação de um sistema de perguntas e respostas, o qual servirá como base para coleta estruturada de informações. Conforme descrito no documento, a aplicação web será construída para que "os usuários inicialmente utilizarão a plataforma de perguntas e respostas e, futuramente, migrarão para a interação com a IA".…
O projeto propõe o desenvolvimento e validação pré-clínica do ImmunoClor, uma nanoimunoterapia intravesical inédita voltada ao tratamento do câncer de bexiga não-músculo invasivo (CBNMI) não-responsivo ao BCG, uma condição clínica de difícil manejo, associada à alta taxa de recorrência, limitação terapêutica e significativa deterioração da qualidade de vida dos pacientes. O ImmunoClor é c…
(Only some records are available in English at this moment)
Os métodos atuais para a fabricação de pranchas de surfe apresentam ineficiência quando se trata de sustentabilidade, devido à geração de resíduos, ao baixo aproveitamento do material base e à resistência mecânica limitada, uma vez que as pranchas não possuem uma estrutura interna adequada. Além disso, há a escolha de materiais mais frágeis e derivados do petróleo. Esses fatores geram uma…
Os produtores de resíduos enfrentam desafios significativos ao buscar métodos eficazes para promover a reutilização dos materiais descartados. Por outro lado, os artesãos e as oficinas encontram dificuldades para comercializar seus produtos upcycling, ao mesmo tempo em que lidam com os desafios da gestão do processo. Para proporcionar uma melhoria nesse processo, o projeto ciclou propõe …
O mesmo tem como objetivo responder desafios de mercado, processos, estratégia e gestão comercial presentes no desenvolvimento da empresa Diasci e a inserção no mercado dodispositivo inovador criado pelos pesquisadores responsáveis. Tal dispositivo foi previamente desenvolvido com o intuito de criar um exame minimamente invasivo para avaliação de biomarcadores tumorais presentes no sangue…
(Only some records are available in English at this moment)
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