- Research Grants
The agreement with the Cardiff University, UK, aims to implement scientific and technological cooperation between researchers from the State of São Paulo and researchers from Cardiff, through the funding of joint research projects.
In this project, several metal-based compounds will be systematically developed and evaluated to selectively target zinc finger domains (ZF). Based on the recent report that organometallic gold(III) cyclometalated compounds can selectively target PARP-1 ZF domains in a combination of Cys3His (PARP-1) with Cys2His2 (commonly found in transcription factor), we propose to rationalize the s...
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