Innovative Research in Small Business (PIPE) Phase 2 - Current Projects

• Abstract

  The present project aims at scaling up an innovative microwave-based extraction system for the continuous production of natural extracts. The validation of this technology will be carried out using Jambu to obtain alcoholic extracts enriched with spilanthol. The proposed technology seeks to overcome the limitations of conventional methods and enhance the efficiency of industrial extractio…

  Development of a system for the production of Jambu alcoholic extract concentrated in spilanthol based on a multimode microwave cavity at a semi-industrial scale for continuous processing, AP.PIPE

• Abstract

  Medulloblastoma is the most common malignant central nervous system tumor in children, with an estimated 30,000 children affected worldwide each year. According to the World Health Organization (WHO), this tumor is molecularly subdivided into four subgroups: WNT, SHH (wild-type TP53 or mutated TP53), and Non-WNT/SHH (Group 3 and 4). These subgroups have distinct molecular and clinical cha…

  Multicenter Validation and Automation of the NEOPROFILER-MB Prototype, a Molecular Test for Medulloblastoma Classification Based on RT-qPCR Technology and Artificial Intelligence., AP.PIPE

• Abstract

  In 2020, approximately nineteen million three hundred thousand new cancer cases were reported worldwide, resulting in ten million deaths attributed to the disease. While developed countries have seen a gradual reduction in mortality rates, the same cannot be said for developing nations where socio-economic disparities are more evident. The growing global population and increased life expe…

  Direct Detection of Circulating Tumor Cells in the Peripheral Blood, AP.PIPE

(Only some records are available in English at this moment)

• Gamified application with ventilatory biofeedback for monitoring and optimizing attention in ADHD: dynamic clinical platform, BP.PIPE
• Commercial structuring for market entry of the project involving a catheter equipped with UV-C LEDs for the disinfection of walls and water in hemodialysis ducts, BP.PIPE
• Development of variants of a commercial reverse transcriptase with enhanced thermal stability, BP.PIPE

(Only some records are available in English at this moment)