The purpose of this initiative, Scholarships to Stimulate Scientific Vocations, is to allow undergraduate students to do internships at a Research Institution, being obligatorily received by a researcher who is a full member of the Brazilian Academy of Sciences. The student must keep in touch with a scientific project in progress and must help in its execution, as appropriate.
Maintaining genomic stability is crucial for cell survival and is ensured by complex DNA repair systems. Defects in these mechanisms are associated with various pathologies, including chromosomal instability syndromes and cancer predisposition. Cells deficient in nucleotide excision repair become hypersensitive to DNA-damaging agents. This project aims to investigate the cellular response…
Extracellular vesicles (EVs) represent a crucial mechanism of non-classical intercellular communication, transporting a complex molecular cargo (proteins, miRNAs, etc.) that modulates the function of recipient cells, being considered "liquid biopsies" of the cellular state. In the context of cryptococcosis (Cryptococcus neoformans), the pathogen-host interaction is bidirectional, and alth…
Organophosphates are highly toxic and exhibit high chemical stability, justifying their use in pesticides and chemical weapons. Our group has focused on developing catalysts for the degradation of these compounds, as well as their detection. Carbon nanomaterials derived from graphene have proven promising supports for nanocatalysts. Graphene oxide's two-dimensional structure contains oxyg…
(Only some records are available in English at this moment)
Professor Paulo Antônio de Souza Mourão's group (UFRJ) is studying the antitumor, antimetastatic, and antithrombotic properties of sulfated fucans from marine invertebrates. The fucan FucSulf2, isolated from the sea cucumber Holothuria grisea, demonstrated antitumor and potentially anti-angiogenic activity in prostate and melanoma tumor cells, inhibiting tumor growth in vivo (with results…
The main focus of the research developed by our group is the identification and validation of biomarkers and therapeutic targets that can enhance the personalization of cancer treatments, which is defined as precision oncology. Breast cancer (BC) is the most common cancer among women worldwide, with excess adiposity being an extrinsic factor linked to its development, associated with the …
The relevance of this project lies in the challenge of treating degenerative retinal diseases, in which the death of the cells that constitute its layers does not trigger repopulation mechanisms in mammals. Given this scenario, a promising strategy for regenerating these neurons is the reprogramming of retinal Müller cells (MG)-a process that can be stimulated, in mouse models and in conj…
(Only some records are available in English at this moment)
One of the research lines of the NuBBE group (Nucleus of Biosynthesis, Bioassays, and Ecophysiology of Natural Products) of the Chemistry Institute of Araraquara (UNESP) is related to the discovery of new cyclic peptides produced by plants, an area of research in natural products still unexplored in Brazil and initiated at NuBBE, with funding from FAPESP Program CEPID - Center for Researc…
The project aims to conduct a systematic literature review on the relationship between strategies and practices in early childhood education and language development during early childhood. The research seeks to identify approaches, interventions, and outcomes described in the literature, providing a knowledge base for educators and policymakers in the field of early childhood education.
The student's internship at the Federal University of Ceará is expected to begin in July 2025. Until then, the scholarship student will be involved in a project aimed at identifying the cross-reactivity of T-cell receptors (TCRs) through the structural analysis of antigenic peptides. Cross-reactivity occurs when a TCR is capable of recognizing multiple different peptides, leading to diver…
(Only some records are available in English at this moment)
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