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VIDA-FROG: Valorization of Molecules Isolated from Aquatic Portuguese Amphibians

Grant number:18/07999-7
Support Opportunities:Regular Research Grants
Start date: May 01, 2019
End date: December 31, 2022
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Agreement: Fundação para a Ciência e a Tecnologia (FCT)
Principal Investigator:Massuo Jorge Kato
Grantee:Massuo Jorge Kato
Principal researcher abroad:Peter Jonathan Eaton
Institution abroad: Universidade do Porto (UP) , Portugal
Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
City of the host institution:São Paulo
Associated researchers: José Roberto de Souza de Almeida Leite
Associated scholarship(s):19/27661-3 - "Bioactive Peptides from Aquatic Portuguese Amphibians", BP.PD

Abstract

The objective of this study is the integration of experiences in the identification and characterization of bioactive compounds (peptides from animal origin and secondary compounds from plants). Studies involving synergism between peptides and amides based on natural products may contribute to understand structure-activity relationship and to the describe biological processes involved in the control of microrganisms, parasites and cell growth. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications (4)
(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)
HAMED, ABDELAATY; YAMAGUCHI, LYDIA FUMIKO; MORANTE, ESTELA YNES VALENCIA; SPIRA, BENY; STAMMLER, HANS GEORG; EL GAAFARY, MENNA; ZIEGLER, DAVID; SYROVETS, TATIANA; SIMMET, THOMAS; KATO, MASSUO JORGE. Cannabinoid-like meroterpenoids from Peperomia incana. Phytochemistry, v. 207, p. 12-pg., . (14/50316-7, 19/27661-3, 18/07999-7)
BARROS, ANA L. A. N.; HAMED, ABDELAATY; MARANI, MARIELA; MOREIRA, DANIEL C.; EATON, PETER; PLACIDO, ALEXANDRA; KATO, MASSUO J.; LEITE, JOSE ROBERTO S. A.. he Arsenal of Bioactive Molecules in the Skin Secretion of Urodele Amphibian. FRONTIERS IN PHARMACOLOGY, v. 12, . (18/07999-7)
BARBOSA, EDER ALVES; PLACIDO, ALEXANDRA; MOREIRA, DANIEL C.; ALBUQUERQUE, LUCAS; DEMATEI, ANDERSON; SILVA-CARVALHO, AMANDDA E.; CABRAL, WANESSA F.; BAO, SONIA N.; SALDANHA-ARAUJO, FELIPE; KUCKELHAUS, SELMA A. S.; et al. The peptide secreted at the water to land transition in a model amphibian has antioxidant effects. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, v. 288, n. 1962, . (18/07999-7)
HAMED, ABDELAATY; EL GAAFARY, MENNA; FUMIKO YAMAGUCHI, LYDIA; STAMMLER, HANS GEORG; SALIH, LAYTH M.; ZIEGLER, DAVID; SYROVETS, TATIANA; KATO, MASSUO JORGE. Chemical constituents of Coccoloba peltata Schott leaves and their cytotoxic activities. NATURAL PRODUCT RESEARCH, v. N/A, p. 7-pg., . (18/07999-7, 19/27661-3, 14/50316-7)