Functionalization of 1-Iodoglucal Derived from D-Glucal Employing the Carbonylative Coupling Reaction

• Grant number: 23/10652-7
• Support Opportunities: Regular Research Grants
• Start date: February 01, 2024
• End date: January 31, 2026
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Helio Alexandre Stefani
• Grantee: Helio Alexandre Stefani
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The project has as its main focus the use of 1-iodoglucal in transformations involving carbonylative coupling reactions and cyclization reactions. It is also intended, whenever possible, to evaluate the biological activity of the prepared compounds (antifungal, anticancer and anti-inflammatory activity). (AU)