Advanced search
Start date
Betweenand

PLACENTAL INTEGRATIVE OMICS APPROACH RELATED TO BREAST CANCER DURING PREGNANCY

Abstract

The SPRINT proposal will be a great opportunity to establish a collaborative partnership between Dr. Laís Rosa Viana from Unicamp - Principal Investigator of the Young Researcher (FAPESP process #2021/08931-0) and Regular Research (FAPESP process #2023/01310-5) Projects - and Dr. Olivier E. Pardo from Imperial College London - Principal Investigator of the multiple funded projects, including the BCRT/8121 project on FGF2 signalling in osteosarcoma and the WCR23-0026 project on RSK isoform-specific signalling. This partnership will involve the placental omics profiling (transcriptomics, miRomics, proteomics and metabolomics) of pregnant patients with breast cancer. The profiling will be performed by Dr. Viana's group and the subsequent omics data integration in collaboration with Dr. Pardo's group. The exchange activities related to this proposal will include: 1) those aiming to contribute to the communities of both Institutions, with a focus on postgraduate students and 2) exchange activities promoting the ongoing research in Brazil and the Partner Institution. These exchange activities will be carried out by the principal investigators and a post-doctoral researcher will be divided as part of 4 missions along 24 months. The results obtained during these exchanges will form the basis for future medium/long-term collaborative funding applications assessing the signalling crosstalk between trophoblasts and breast cancer cells to predict novel targeted therapies for pregnant breast cancer patients. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
More itemsLess items
Articles published in other media outlets ( ):
More itemsLess items
VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)