Evaluation of the Listeria monocytogenes vaccine vector Lm3Dx_SAG1_ROP2_GRA7 in the prevention of N. caninum induced abortion in cattle.

• Grant number: 24/21110-3
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2025
• End date: July 31, 2027
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Lilian Gregory
• Grantee: Lilian Gregory
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: Andrew Hemphill ; Anna Oevermann ; Liria Hiromi Okuda

Abstract

Brazil has one of the largest cattle herds in the world and its livestock still faces serious losses due to Neospora caninum infection, which causes significant reproductive losses in herds. This project aims to develop a vaccine for Neospora caninum using attenuated Listeria monocytogenes vaccine vector to prevent these losses. (AU)