Experimental transplant of liver and hepatic regeneration

• Grant number: 96/01560-2
• Support Opportunities: Research Projects - Thematic Grants
• Start date: August 01, 1996
• End date: July 31, 2004
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Orlando de Castro e Silva Junior
• Grantee: Orlando de Castro e Silva Junior
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

This project aims to study the effect of laser and conventional light with different powers and exposure times on hypothermically preserved livers for transplant and in remaining livers after partial hepatectomies. Given the results previously obtained in this laboratory it is hoped that the stimulant effect of hepatic regeneration with low-power laser may protect the liver to be transplanted, following different preservation times, from the lesions caused by hypothermia 'per se' and by ischemia and subsequent reperfusion. (AU)