Structural biology of proteins that may the be targets of insect control strategies

• Grant number: 01/07531-4
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2001
• End date: December 31, 2005
• Field of knowledge: Biological Sciences - Biochemistry
• Principal Investigator: Walter Ribeiro Terra
• Grantee: Walter Ribeiro Terra
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Four types of insect proteins have been selected and the resolution of their structures are expected to be reavealing. The proteins are: beta-glycosidases, digestive lysozymes, trypsins and peritrophins. These proteins are being studied in our laboratory and we have cloned and expressed one of the beta-glycosidases, we have clones of lysozymes and some trypsins and one peritrophin have been purified to homogeneity. We are also interested in helping to study proteins coded by genomes of Brazilian interest. We are particularly interested in glycoside hydrolases and peptide hydrolases and their protein inhibitors. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CANCADO, F. C.; EFFIO, P. CHIMOY; TERRA, W. R.; MARANA, S. R.. Cloning, purification and comparative characterization of two digestive lysozymes from Musca domestica larvae. Brazilian Journal of Medical and Biological Research, v. 41, n. 11, p. 969-977, NOV 2008. (01/07531-4)