Relationship between upper eyelid saccades and blinks in the Graves upper eyelid retraction

• Grant number: 07/00227-4
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2007
• End date: July 31, 2008
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Antonio Augusto Velasco e Cruz
• Grantee: Antonio Augusto Velasco e Cruz
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Graves orbitopathy is an autoimmune condition characterized by restrictive extraocular myopathy, upper eyelid retraction and proptosis. The combination of eye displacement and upper eyelid retraction put at risk the ocular surface and the patients affected usually have exposure keratitis. On the other hand, the mechanisms involved in the upper eyelid retraction have not been fully understood and there are no studies on the dynamics of the retracted upper eyelid. This main aim of the present research is to quantify the relationship between the upper eyelid saccades and the blinks of patients with Graves upper eyelid retraction utilizing the magnetic search coil technique. The results of this study will allow the isolation of the passive and active components of the upper eyelid retraction in Graves orbitopathy. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GARCIA‚ D.M.; MESSIAS‚ A.; COSTA‚ L.O.; PINTO‚ C.T.; BARBOSA‚ J.C.; VELASCO CRUZ‚ A.A.. Spontaneous blinking in patients with Graves’ upper eyelid retraction. CURRENT EYE RESEARCH, v. 35, n. 6, p. 459-465, 2010. (07/00227-4)