The efficacy of neurophysiological monitoring during endovascular neurologic procedures

• Grant number: 10/16929-0
• Support Opportunities: Regular Research Grants
• Start date: May 01, 2011
• End date: October 31, 2013
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Gilmar Fernandes Do Prado
• Grantee: Gilmar Fernandes Do Prado
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated researchers: Carmelinda Correia de Campos ; Denise Spinola Pinheiro ; Gilberto Mastrocola Manzano ; Nadia Iandoli de Oliveira Braga

Abstract

The goal of endovascular neurosurgery is to occlude aneurysms and arteriovenous malformations (AVMs) or reduce the vascular supply to hypervascularized tumors, while preserving normal function of neural tissue. When these procedures are performed using general anesthesia, neurophysiological monitoring is the only method to access the functional integrity of cortex, sensory and motor pathways, and auditory system. The neurophysiological monitoring can alert the neuroradiologist and avoid irreversible neurological damage since an adequate perfusion is restored in time. The purpose of this study is to evaluate the effectiveness of multimodal neurophysiologic monitoring in detecting ischemia during endovascular treatment of cerebral aneurysms, carotid stenosis and arteriovenous malformations. With this objective we will to record EEG, SSEP, MEP and PEATEC to study the neural structures at risk and determine the sensitivity of each method in the protection of structures monitored during the procedure. (AU)